U - Intracellular trafficking, secretion, and vesicular transport

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COG definitions	Organims	Proteins	Median Protein Length	Genes
109	1,303	62,030	322.0	99

Organism	Protein	COG	Cat	Annotation
1298	1320	COG0201	U	Preprotein translocase subunit SecY
1153	1213	COG0341	U	Preprotein translocase subunit SecF
1156	1254	COG0342	U	Preprotein translocase subunit SecD
1261	1261	COG0541	U	Signal recognition particle GTPase
1241	1241	COG0552	U	Signal recognition particle GTPase FtsY
1147	1325	COG0597	M U	Lipoprotein signal peptidase
175	402	COG0630	N U	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI
1169	1311	COG0653	U	Preprotein translocase subunit SecA (ATPase, RNA helicase)
1070	1072	COG0658	U	DNA uptake channel protein ComEC, N-terminal domain
1188	1717	COG0681	U	Signal peptidase I
1077	1068	COG0690	U	Preprotein translocase subunit SecE
1053	1164	COG0805	U	Twin-arginine protein secretion pathway component TatC
802	2429	COG0811	U	Biopolymer transport protein ExbB/TolQ
832	2129	COG0823	U	Periplasmic component TolB of the Tol biopolymer transport system
774	2551	COG0848	U	Biopolymer transport protein ExbD
75	75	COG1096	U	Exosome complex RNA-binding protein Csl4, contains S1 and Zn-ribbon domains
75	75	COG1097	U	Exosome complex RNA-binding protein Rrp4, contains S1 and KH domains
614	751	COG1157	N U	Flagellar biosynthesis/type III secretory pathway ATPase FliI
640	683	COG1272	U	Predicted membrane channel-forming protein YqfA, hemolysin III family
817	814	COG1314	U	Protein translocase subunit SecG
508	590	COG1317	N U	Flagellar biosynthesis/type III secretory pathway protein FliH
108	111	COG1325	U	Exosome subunit, RNA binding protein with dsRBD fold
116	116	COG1400	U	Signal recognition particle subunit SEC65
501	992	COG1450	U	Type II secretory pathway component GspD/PulD (secretin)
763	1480	COG1459	N W U	Type II secretory pathway, component PulF
492	557	COG1516	N U	Flagellin-specific chaperone FliS
592	652	COG1766	N U	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ
1018	1895	COG1826	U	Twin-arginine protein secretion pathway components TatA and TatB
115	116	COG1855	W U	Predicted ATPase, PilT family, contains N-terminal PIN domain
1047	1051	COG1862	U	Protein translocase subunit YajC
617	866	COG1886	N U	Flagellar motor switch/type III secretory pathway protein FliN
482	493	COG1952	U	Preprotein translocase subunit SecB
727	786	COG1989	N U	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase
78	79	COG2123	U	Exosome complex RNA-binding protein Rrp42, RNase PH superfamily
656	3374	COG2165	N W U	Type II secretory pathway, pseudopilin PulG
200	482	COG2229	U	Signal recognition particle receptor subunit beta, a GTPase
284	294	COG2257	U	Type III secretion system substrate exporter, FlhB-like
796	1074	COG2333	U	DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily
102	102	COG2443	U	Preprotein translocase subunit Sss1
764	1768	COG2804	N W U	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB
335	665	COG2831	U	Hemolysin activation/secretion protein
195	356	COG2948	U	Type IV secretory pathway, VirB10 component
172	200	COG3031	U	Type II secretory pathway, component PulC
198	202	COG3114	U	Heme exporter protein D
154	162	COG3149	U	Type II secretory pathway, component PulM
290	334	COG3156	U	Type II secretory pathway, component PulK
214	458	COG3157	U	Type VI protein secretion system component Hcp (secreted cytotoxin)
255	845	COG3210	U	Large exoprotein involved in heme utilization or adhesion
338	631	COG3267	W U	Type II secretory pathway ATPase component GspA/ExeA/MshM
105	129	COG3271	U	Predicted double-glycine leader peptidase, C39-like (CLD) domain
173	178	COG3297	U	Type II secretory pathway, component PulL
162	171	COG3418	N U	Flagellar biosynthesis/type III secretory pathway chaperone FlgN
520	983	COG3451	U	Type IV secretory pathway, VirB4 component
202	290	COG3455	U	Type VI protein secretion system component TssL/VasF/DotU
152	182	COG3456	T U	Predicted component of the type VI protein secretion system, contains a FHA domain
110	375	COG3468	M U	Autotransporter adhesin AidA
309	991	COG3501	U X R	Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly
180	345	COG3504	U	Type IV secretory pathway, VirB9 components
556	1138	COG3505	U	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase
188	288	COG3515	U	Type VI protein secretion system component TssA1/VasJ/EvfE, contains ImpA_N domain
201	292	COG3516	U	Predicted component TssA of the type VI protein secretion system
199	331	COG3517	U	Predicted component TssB of the type VI protein secretion system, VipA/VipB/TssB family
197	263	COG3518	U	Predicted component of the type VI protein secretion system
197	281	COG3519	U	Type VI protein secretion system component VasA
199	272	COG3520	U	Predicted component of the type VI protein secretion system
154	215	COG3521	U	Type VI secretion system component TssJ/Cytochrome oxidase assembly protein CtaK
205	285	COG3522	U	Predicted component of the type VI protein secretion system
197	306	COG3523	U	Type VI protein secretion system component VasK
117	158	COG3559	U	Putative exporter of oligosaccharides and polyketide antibiotics DrrB/NodJ, ABC-2 family
120	209	COG3701	U	Type IV secretory pathway, TrbF component
94	116	COG3702	U	Type IV secretory pathway, VirB3 component
98	166	COG3704	U	Type IV secretory pathway, VirB6 component
94	133	COG3736	U	Type IV secretory pathway, component VirB8
342	452	COG3745	W U	Flp pilus assembly protein CpaB
125	236	COG3838	U	Type IV secretory pathway, VirB2 component (pilin)
92	171	COG3843	U	Type IV secretory pathway, VirD2 component (relaxase)
114	189	COG3846	U	Type IV secretory pathway, TrbL components
200	372	COG3847	W U	Flp pilus assembly protein, pilin Flp
120	134	COG3913	T U	Regulator of T6SS expression TagF, TagF/ImpM/SciT family (unrelated to teichoic acid polymerase TagF of B.subtilis, COG1887)
61	72	COG3946	U	Type IV secretory pathway, VirJ component
93	93	COG4023	U	Preprotein translocase subunit SecG (Sec61beta)
58	61	COG4083	U	Exosortase/Archaeosortase
217	448	COG4104	U	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, involved in Type VI secretion
73	79	COG4473	U	Predicted ABC-type exoprotein transport system, permease component
25	25	COG4499	U	ESX protein secretion system component YukC
181	284	COG4618	U	ABC-type protease/lipase transport system, ATPase and permease components
82	111	COG4669	U	Type III secretory pathway, lipoprotein EscJ
81	110	COG4789	U	Type III secretory pathway, component EscV
80	108	COG4790	U	Type III secretory pathway, EscR/YscR component
75	96	COG4791	U	Type III secretory pathway, EscT/YscT component
27	31	COG4792	U	Type III secretory pathway, EscU/YscU component
69	91	COG4794	U	Type III secretory pathway, EscS/YscS component
323	400	COG4795	U	Type II secretory pathway, PulJ/GspJ component
365	407	COG4796	U	Type II secretory pathway, component HofQ
287	410	COG4959	U O	Type IV secretory pathway, protease TraF
277	706	COG4961	W U	Flp pilus assembly protein TadG, includes N-terminal TadE domain
581	1133	COG4962	W U	Pilus assembly protein, ATPase of CpaF family
310	398	COG4963	W U	Flp pilus assembly ATPase CpaE/TadZ, contains N-terminal REC/TadZ_N domain
259	373	COG4964	W U	Flp pilus assembly protein, secretin CpaC
494	850	COG4965	W U	Flp pilus assembly protein TadB
786	2111	COG5010	W U	Flp pilus assembly protein TadD, contains TPR repeats
27	27	COG5036	U P	SPX domain-containing protein involved in vacuolar polyphosphate accumulation
4	4	COG5153	U	Putative lipase ATG15 (essential for vacuolar disintegration of autophagic bodies)
102	178	COG5268	U	Type IV secretory pathway, TrbD component
104	250	COG5295	W U	Autotransporter adhesin
30	32	COG5407	U	Preprotein translocase subunit Sec63
18	18	COG5417	U	ESX protein secretion system component YukD
12	15	COG5555	U	Cytolysin, a secreted calcineurin-like phosphatase
17	17	COG5613	U	Type III secretion system effector SseC (host membrane pore formation)