E - Amino acid transport and metabolism

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COG definitions	Organims	Proteins	Median Protein Length	Genes
291	2,296	532,682	357.0	286

Organism	Protein	COG	Cat	Annotation
1867	1963	COG0002	E	N-acetyl-gamma-glutamylphosphate reductase
2212	5179	COG0006	E	Xaa-Pro aminopeptidase
1495	3050	COG0010	E	Arginase/agmatinase family enzyme
1721	1827	COG0014	E	Gamma-glutamyl phosphate reductase
2035	3493	COG0019	E	Diaminopimelate decarboxylase
1982	5797	COG0028	E H	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme
2072	4584	COG0031	E	Cysteine synthase
1899	1931	COG0040	E	ATP phosphoribosyltransferase
1880	1948	COG0059	E H	Ketol-acid reductoisomerase
1890	2368	COG0065	E	Homoaconitase/3-isopropylmalate dehydratase large subunit
1896	2357	COG0066	E	3-isopropylmalate dehydratase small subunit
1677	1918	COG0067	E	Glutamate synthase domain 1
1796	2825	COG0069	E	Glutamate synthase domain 2
1682	1948	COG0070	E	Glutamate synthase domain 3
1305	1976	COG0075	E F	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG
1029	1743	COG0076	E	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein
1944	2038	COG0077	E	Prephenate dehydratase
2051	2400	COG0078	E	Ornithine carbamoyltransferase
2028	4210	COG0079	E	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase
2070	2095	COG0082	E	Chorismate synthase
1099	1111	COG0083	E	Homoserine kinase
1905	1954	COG0106	E	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
1921	2097	COG0107	E	Imidazole glycerol phosphate synthase subunit HisF
2204	2580	COG0112	E	Glycine/serine hydroxymethyltransferase
2079	4990	COG0115	E H	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
1903	2037	COG0118	E	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH
1983	5326	COG0119	E	Isopropylmalate/homocitrate/citramalate synthases
2084	2172	COG0128	E	5-enolpyruvylshikimate-3-phosphate synthase
1889	3508	COG0129	G E	Dihydroxyacid dehydratase/phosphogluconate dehydratase
1897	1904	COG0131	E	Imidazoleglycerol phosphate dehydratase HisB
1895	2143	COG0133	E	Tryptophan synthase beta chain
1881	1960	COG0134	E	Indole-3-glycerol phosphate synthase
1707	1841	COG0135	E	Phosphoribosylanthranilate isomerase
2124	2391	COG0136	E	Aspartate-semialdehyde dehydrogenase
1933	1975	COG0137	E	Argininosuccinate synthase
1898	1954	COG0139	E	Phosphoribosyl-AMP cyclohydrolase
1744	1777	COG0140	E	Phosphoribosyl-ATP pyrophosphohydrolase
1890	2157	COG0141	E	Histidinol dehydrogenase
952	1914	COG0145	E Q	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit
763	1411	COG0146	E Q	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit
1952	3586	COG0147	E H	Anthranilate/para-aminobenzoate synthases component I
1893	1962	COG0159	E	Tryptophan synthase alpha chain
1184	2353	COG0160	E	Acetylornithine aminotransferase/4-aminobutyrate aminotransferase/amino acid racemase
1946	2131	COG0165	E	Argininosuccinate lyase
2090	2685	COG0169	E	Shikimate 5-dehydrogenase
1950	3902	COG0174	E	Glutamine synthetase
1566	3102	COG0175	E H	Phosphoadenylyl sulfate (PAPS) reductase/FAD synthetase or related enzyme
971	1021	COG0182	E	5-methylthioribose/5-deoxyribulose 1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit
1589	3446	COG0189	J E H Q	Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily
1584	3103	COG0235	G E	5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation)
1116	1430	COG0241	E	Histidinol phosphatase/D-glycero-mannoheptose bisphosphatephosphatase, HAD superfamily
1376	1707	COG0252	J E	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
1915	2015	COG0253	E	Diaminopimelate epimerase
1540	2232	COG0260	E	Leucyl aminopeptidase
1729	1814	COG0263	E	Glutamate 5-kinase
1925	2015	COG0287	E	Prephenate dehydrogenase
2018	2104	COG0289	E	4-hydroxy-tetrahydrodipicolinate reductase
1512	3308	COG0308	E	Aminopeptidase N, contains DUF3458 domain
2114	5103	COG0329	M E	4-hydroxy-tetrahydrodipicolinate synthase/N-acetylneuraminate lyase
1713	2914	COG0334	E	Glutamate dehydrogenase/leucine dehydrogenase
1923	2152	COG0337	E	3-dehydroquinate synthetase
1957	2328	COG0345	E	Pyrroline-5-carboxylate reductase
1589	3120	COG0347	T E	Nitrogen regulatory protein PII
1488	2988	COG0367	E	Asparagine synthetase B (glutamine-hydrolyzing)
1641	1720	COG0403	E	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
1707	3245	COG0404	E	Glycine cleavage system protein T (aminomethyltransferase)
1319	2521	COG0405	E	Gamma-glutamyltranspeptidase
1302	5351	COG0410	E	ABC-type branched-chain amino acid transport system, ATPase component LivF
1218	4729	COG0411	E	ABC-type branched-chain amino acid transport system, ATPase component LivG
1427	2351	COG0421	E	Spermidine synthase (polyamine aminopropyltransferase)
2171	8558	COG0436	E	Aspartate/methionine/tyrosine aminotransferase
1790	1970	COG0440	E	Acetolactate synthase, small subunit
1474	8269	COG0444	E P	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
2042	2719	COG0458	E F	Carbamoylphosphate synthase large subunit
1996	2377	COG0460	E	Homoserine dehydrogenase
1958	3176	COG0473	C E	Isocitrate/isopropylmalate dehydrogenase
846	2343	COG0477	G E P R	MFS family permease, includes anhydromuropeptide permease AmpG
1785	4090	COG0493	E R	NADPH-dependent glutamate synthase beta chain or related oxidoreductase
2015	2871	COG0498	E	Threonine synthase
2021	2150	COG0505	E F	Carbamoylphosphate synthase small subunit
1361	1521	COG0506	E	Proline dehydrogenase
1784	2127	COG0509	E	Glycine cleavage system protein H (lipoate-binding)
1937	2515	COG0512	E H	Anthranilate/para-aminobenzoate synthase component II (glutamine amidotransferase)
1975	4163	COG0520	E	Selenocysteine lyase/Cysteine desulfurase
2122	3290	COG0527	E	Aspartate kinase
1739	6620	COG0531	E	Serine and glutamate transporter AimA/YbeC, amino acid:H+ symporter family
1875	2363	COG0547	E	Anthranilate phosphoribosyltransferase, glycosyltransferase domain
1852	2346	COG0548	E	N-acetylglutamate kinase
528	653	COG0549	E	Carbamate kinase
1293	5367	COG0559	E	Branched-chain amino acid ABC-type transport system, permease component
1608	2928	COG0560	E	Phosphoserine phosphatase
1627	4270	COG0591	E	Na+/proline symporter
1824	8432	COG0601	E P	ABC-type dipeptide/oligopeptide/nickel transport system, permease component
1193	1793	COG0620	E	Methionine synthase II (cobalamin-independent)
2040	8023	COG0624	E	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase
1672	3840	COG0626	E	Cystathionine beta-lyase/cystathionine gamma-synthase
1573	1854	COG0646	E	Methionine synthase I (cobalamin-dependent), methyltransferase domain
1770	8471	COG0665	E	Glycine/D-amino acid oxidase (deaminating)
1606	8381	COG0683	E	ABC-type branched-chain amino acid transport system, periplasmic component
1801	2271	COG0685	E	5,10-methylenetetrahydrofolate reductase
1257	1685	COG0686	E	Alanine dehydrogenase (includes sporulation protein SpoVN)
1160	3064	COG0687	E	Spermidine/putrescine-binding periplasmic protein
2068	13867	COG0697	G E R	Permease of the drug/metabolite transporter (DMT) superfamily
1964	2378	COG0703	E	Shikimate kinase
839	866	COG0709	E	Selenophosphate synthase
502	530	COG0710	E	3-dehydroquinate dehydratase
769	1130	COG0722	E	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
1802	9317	COG0747	E	ABC-type transport system, periplasmic component
356	409	COG0754	E	Glutathionylspermidine synthase, CHAP domain
1620	1754	COG0757	E	3-dehydroquinate dehydratase
1444	6676	COG0765	E	ABC-type amino acid transport system, permease component
401	506	COG0786	E	Na+/glutamate symporter
672	726	COG0804	E	Urease alpha subunit
258	709	COG0814	E	Amino acid permease
678	736	COG0831	E	Urease gamma subunit
665	721	COG0832	E	Urease beta subunit
320	474	COG0833	E	Amino acid permease
1767	11106	COG0834	T E	ABC-type amino acid transport/signal transduction system, periplasmic component/domain
1642	1723	COG1003	E	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
679	776	COG1027	E	Aspartate ammonia-lyase
1834	2847	COG1045	E	Serine acetyltransferase
1667	5740	COG1063	E R	Threonine dehydrogenase or related Zn-dependent dehydrogenase
2008	3387	COG1104	E	Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family
489	1353	COG1113	E	L-asparagine transporter or related permease
472	660	COG1114	E	Branched-chain amino acid permease
1070	1940	COG1115	E	Na+/alanine symporter
464	690	COG1124	E P	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
777	995	COG1125	E	ABC-type proline/glycine betaine transport system, ATPase component
1467	4710	COG1126	E	ABC-type polar amino acid transport system, ATPase component
1037	1482	COG1135	E	ABC-type methionine transport system, ATPase component
1053	1667	COG1164	E	Oligoendopeptidase F
676	690	COG1166	E	Arginine decarboxylase (spermidine biosynthesis)
1484	4772	COG1167	K E	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain
853	1083	COG1168	E R	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
1729	3274	COG1171	E	Threonine deaminase
1810	8376	COG1173	E P	ABC-type dipeptide/oligopeptide/nickel transport system, permease component
809	1651	COG1174	E	ABC-type proline/glycine betaine transport system, permease component
1117	2718	COG1176	E	ABC-type spermidine/putrescine transport system, permease component I
1160	3056	COG1177	E	ABC-type spermidine/putrescine transport system, permease component II
611	990	COG1231	E	Monoamine oxidase
1611	3257	COG1246	E	N-acetylglutamate synthase or related acetyltransferase, GNAT family
1507	3394	COG1247	E	L-amino acid N-acyltransferase MnaT
638	673	COG1279	E	Arginine exporter protein ArgO
1413	4861	COG1280	E	Threonine/homoserine/homoserine lactone efflux protein
1097	1401	COG1296	E	Predicted branched-chain amino acid permease (azaleucine resistance)
434	463	COG1350	E	Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB)
546	667	COG1362	E	Aspartyl aminopeptidase
944	1662	COG1363	G E	Putative aminopeptidase FrvX
1423	1450	COG1364	E	Glutamate N-acetyltransferase (ornithine transacetylase)
1098	1897	COG1387	E R	Histidinol phosphatase or related hydrolase of the PHP family
1549	1893	COG1410	E	Methionine synthase I, cobalamin-binding domain
718	922	COG1446	E	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily
585	755	COG1448	E	Aspartate/aromatic aminotransferase
187	192	COG1465	E	3-dehydroquinate synthase, class II
630	756	COG1505	E	Prolyl endopeptidase PreP, S9A serine peptidase family
1645	6944	COG1506	E	Dipeptidyl aminopeptidase/acylaminoacyl peptidase
921	1185	COG1509	E	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)
875	998	COG1540	E	5-oxoprolinase subunit A
865	985	COG1586	E	S-adenosylmethionine decarboxylase
1869	2437	COG1605	E	Chorismate mutase
142	142	COG1685	E	Archaeal shikimate kinase
182	188	COG1687	E	Branched-chain amino acid transport protein AzlD
259	292	COG1712	E	L-aspartate dehydrogenase, NAD(P)-dependent
955	1242	COG1748	E	Saccharopine dehydrogenase, NADP-dependent
1301	1879	COG1760	E	L-serine deaminase
673	763	COG1770	E	Protease II
306	705	COG1775	E Q	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB
287	296	COG1791	E	Acireductone dioxygenase (methionine salvage), cupin superfamily
255	269	COG1823	E	L-cystine transporter TcyP, sodium:dicarboxylate symporter family
623	828	COG1834	E	N-Dimethylarginine dimethylaminohydrolase
1069	1767	COG1878	E	Kynurenine formamidase
620	628	COG1897	E	Homoserine O-succinyltransferase
205	243	COG1900	E	Sulfur incorporation enzyme MA1821 (anaerobic homocysteine biosynthesis), HcyBio/DUF39 family
1487	1548	COG1932	E H	Phosphoserine aminotransferase
236	249	COG1945	E	Pyruvoyl-dependent arginine decarboxylase
899	1074	COG1966	C E	Carbon starvation protein CstA (peptide/pyruvate transporter)
797	1182	COG1982	E	Arginine/lysine/ornithine decarboxylase
939	1179	COG1984	E	5-oxoprolinase subunit C/Allophanate hydrolase subunit 2
1262	1479	COG2008	E	Threonine aldolase
886	1246	COG2011	E	ABC-type methionine transport system, permease component
1126	1344	COG2021	E	Homoserine O-acetyltransferase
341	381	COG2040	E	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)
957	1217	COG2049	E	5-oxoprolinase subunit B/Allophanate hydrolase subunit 1
205	225	COG2056	E	Predicted histidine transporter YuiF, NhaC family
651	763	COG2066	E	Glutaminase
985	1275	COG2071	E	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain
1207	1779	COG2095	E	Small neutral amino acid transporter SnatA, MarC family
574	638	COG2105	E	Predicted gamma-glutamylamine cyclotransferase YtfP, GGCT/AIG2-like family
698	1304	COG2113	E	ABC-type proline/glycine betaine transport system, periplasmic component
1491	1547	COG2171	E	Tetrahydrodipicolinate N-succinyltransferase
949	1607	COG2195	E	Di- or tripeptidase
154	156	COG2232	E	Pyrrolysine biosynthesis ligase PylC and related enzymes, ATP-grasp superfamily
980	3008	COG2234	O E	Zn-dependent amino- or carboxypeptidase, M28 family
452	519	COG2235	E	Arginine deiminase
758	1283	COG2309	E	Leucyl aminopeptidase (aminopeptidase T)
980	1477	COG2355	O E	Zn-dependent dipeptidase, microsomal dipeptidase homolog
263	317	COG2362	E	D-aminopeptidase
836	1556	COG2423	E	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family
280	291	COG2431	E	Lysine export protein LysO/YbjE, DUF340 family
292	296	COG2502	E	Asparagine synthetase A
680	809	COG2515	E	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family
422	505	COG2716	E	Glycine cleavage system regulator GcvR
1353	1897	COG2873	E	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent
925	1275	COG2876	E	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
571	619	COG2902	E	NAD-specific glutamate dehydrogenase
315	405	COG2939	E	Carboxypeptidase C (cathepsin A)
685	781	COG2957	E	Agmatine/peptidylarginine deiminase
624	626	COG2981	E P	Sulfate transporter CysZ
969	1300	COG2986	E	Histidine ammonia-lyase
896	947	COG2987	E	Urocanate hydratase
331	378	COG2988	E	Succinylglutamate desuccinylase
293	347	COG3033	E	Tryptophanase
196	202	COG3048	E	D-serine dehydratase
128	128	COG3060	K E	Transcriptional regulator MetJ (met regulon)
199	208	COG3075	E	Anaerobic glycerol-3-phosphate dehydrogenase
777	1311	COG3104	E	Dipeptide/tripeptide permease
251	342	COG3138	E	Arginine/ornithine N-succinyltransferase beta subunit
1033	1468	COG3185	E R	4-hydroxyphenylpyruvate dioxygenase and related hemolysins
391	401	COG3186	E	Phenylalanine-4-hydroxylase
667	871	COG3191	E	L-aminopeptidase/D-esterase
118	131	COG3192	E	Ethanolamine transporter EutH, required for ethanolamine utilization at low pH
628	667	COG3200	E	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II
262	301	COG3232	E	5-carboxymethyl-2-hydroxymuconate isomerase
156	167	COG3283	K E	Transcriptional regulator TyrR of aromatic amino acids metabolism
331	500	COG3314	D E	Spore dipicolinate transporter SpoVV/YjiH/YlbJ, contains nucleoside recognition GATE domain
452	548	COG3340	E	Peptidase E
372	432	COG3404	E	Formiminotetrahydrofolate cyclodeaminase
235	271	COG3457	E	Predicted amino acid racemase
512	564	COG3483	E	Tryptophan 2,3-dioxygenase (vermilion)
223	321	COG3579	E	Aminopeptidase C
699	993	COG3616	E	D-serine deaminase, pyridoxal phosphate-dependent
250	256	COG3633	E	Na+/serine and Na+/threonine symporter SstT
225	249	COG3643	E	Glutamate formiminotransferase
265	317	COG3681	E	L-cysteine desulfidase YhaM
923	923	COG3705	E	ATP phosphoribosyltransferase regulatory subunit HisZ
216	221	COG3724	E	Succinylarginine dihydrolase
517	715	COG3741	E	N-formylglutamate amidohydrolase
88	92	COG3799	E	Methylaspartate ammonia-lyase
1742	5371	COG3842	E	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component
585	621	COG3844	E	Kynureninase
315	421	COG3931	E	Predicted N-formylglutamate amidohydrolase
467	664	COG3938	E	Proline racemase/hydroxyproline epimerase
479	528	COG3968	E	Glutamine synthetase type III
196	201	COG3977	E	Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase
152	152	COG3978	E	Acetolactate synthase small subunit, contains ACT domain
277	330	COG4091	E	Predicted homoserine dehydrogenase, contains C-terminal SAF domain
405	655	COG4126	E	Asp/Glu/hydantoin racemase
344	551	COG4160	E	ABC-type arginine/histidine transport system, permease component
99	100	COG4161	E	ABC-type arginine transport system, ATPase component
1058	2343	COG4166	E	ABC-type oligopeptide transport system, periplasmic component
656	903	COG4175	E	ABC-type proline/glycine betaine transport system, ATPase component
653	915	COG4176	E	ABC-type proline/glycine betaine transport system, permease component
1291	5330	COG4177	E	ABC-type branched-chain amino acid transport system, permease component
127	156	COG4187	E	Citrulline hydrolase RocB
366	587	COG4215	E	ABC-type arginine transport system, permease component
210	214	COG4229	E	Enolase-phosphatase E1 involved in merthionine salvage
619	665	COG4230	E	Delta 1-pyrroline-5-carboxylate dehydrogenase
363	386	COG4302	E	Ethanolamine ammonia-lyase, small subunit
363	389	COG4303	E	Ethanolamine ammonia-lyase, large subunit
275	441	COG4311	E	Sarcosine oxidase delta subunit
274	284	COG4336	E	YcsI protein, probably involved 5-oxoproline metabolism, UPF0317/DUF1446 family
204	220	COG4359	E	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase (methionine salvage)
516	575	COG4392	E	Branched-chain amino acid transport protein
346	351	COG4401	E	Chorismate mutase AroH
130	135	COG4413	E	Urea transporter
478	505	COG4448	E	L-asparaginase II
260	415	COG4583	E	Sarcosine oxidase gamma subunit
406	485	COG4597	E	ABC-type amino acid transport system, permease component
274	347	COG4598	E	ABC-type histidine transport system, ATPase component
561	855	COG4608	E	ABC-type oligopeptide transport system, ATPase component
259	413	COG4690	E	Dipeptidase
143	167	COG4766	E	Ethanolamine utilization protein EutQ, cupin superfamily (function unknown)
118	156	COG4810	E	Ethanolamine utilization protein EutS, microcompartment shell protein
78	88	COG4812	E	Ethanolamine utilization protein EutT, cobalamin adenosyltransferase
122	156	COG4816	E	Ethanolamine utilization protein EutL, microcompartment shell protein
108	119	COG4819	E	Ethanolamine utilization protein EutA, possible chaperonin
112	123	COG4820	E	Ethanolamine utilization protein EutJ, possible chaperonin
242	266	COG4857	E	5-Methylthioribose/5-deoxyribose kinase, methionine salvage pathway
111	118	COG4865	E	Glutamate mutase epsilon subunit
117	151	COG4917	E	Ethanolamine utilization protein EutP, contains a P-loop NTPase domain
1958	3078	COG4992	E	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase
463	598	COG5006	E	Threonine/homoserine efflux transporter RhtA
30	30	COG5630	E	N-acetylglutamate synthase (arginine biosynthesis)
104	104	COG5834	D E	Stage V sporulation protein SpoVAA, subunit of dipicolinate uptake complex
103	103	COG5835	D E	Stage V sporulation protein SpoVAB, subunit of dipicolinate uptake complex
237	276	COG5836	D E	Stage V sporulation protein SpoVAC, subunit of dipicolinate uptake complex
234	275	COG5837	D E	Stage V sporulation protein SpoVAD, subunit of dipicolinate uptake complex
236	271	COG5839	D E	Stage V sporulation protein SpoVAEB, subunit of dipicolinate uptake complex
160	205	COG5840	D E	Stage V sporulation protein SpoVAF, subunit of dipicolinate uptake complex, GerA superfamily
184	190	COG5842	D E	Dipicolinate synthase subunit A (sporulation protein SpoVFA)
187	191	COG5843	D E	Dipicolinate synthase subunit B (sporulation protein SpoVFB)