L - Replication, recombination and repair
Stats
COG definitions |
Organims | Proteins | Median Protein Length |
Genes |
---|---|---|---|---|
189 | 1,309 | 146,012 | 380.0 | 169 |
Organism | Protein | COG | Cat | Annotation |
---|---|---|---|---|
735 | 1018 | COG0122 | L | 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase |
1233 | 1247 | COG0164 | L | Ribonuclease HII |
1230 | 1458 | COG0177 | L | Endonuclease III |
1216 | 1870 | COG0178 | L | Excinuclease UvrABC ATPase subunit |
1243 | 2111 | COG0187 | L | DNA gyrase/topoisomerase IV, subunit B |
1247 | 2132 | COG0188 | L | DNA gyrase/topoisomerase IV, subunit A |
1227 | 2976 | COG0210 | L | Superfamily I DNA or RNA helicase |
1019 | 1349 | COG0249 | L | DNA mismatch repair ATPase MutS |
1284 | 1578 | COG0258 | L | 5'-3' exonuclease Xni/ExoIX (flap endonuclease) |
924 | 1395 | COG0266 | L | Formamidopyrimidine-DNA glycosylase |
648 | 1271 | COG0270 | L | DNA-cytosine methylase |
1187 | 1391 | COG0272 | L | NAD-dependent DNA ligase |
1181 | 1530 | COG0305 | L | Replicative DNA helicase |
1202 | 1553 | COG0322 | L | Excinuclease UvrABC, nuclease subunit |
1018 | 1102 | COG0323 | L | DNA mismatch repair ATPase MutL |
1082 | 1292 | COG0328 | L | Ribonuclease HI |
478 | 713 | COG0338 | L | DNA-adenine methylase |
1159 | 1729 | COG0350 | L | DNA repair enzyme Ada (O6-methylguanine-DNA--protein-cysteine methyltransferase) |
1128 | 1126 | COG0353 | L | Recombinational DNA repair protein RecR |
1290 | 1731 | COG0358 | L | DNA primase (bacterial type) |
1056 | 2020 | COG0389 | L | Nucleotidyltransferase/DNA polymerase DinP involved in DNA repair |
779 | 1071 | COG0415 | L | Deoxyribodipyrimidine photolyase |
318 | 419 | COG0417 | L | DNA polymerase B elongation subunit |
856 | 1249 | COG0419 | L | DNA repair exonuclease SbcCD ATPase subunit |
888 | 1179 | COG0420 | L | DNA repair exonuclease SbcCD nuclease subunit |
811 | 1373 | COG0433 | L | Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains |
1278 | 1463 | COG0468 | L | RecA/RadA recombinase |
700 | 819 | COG0470 | L | DNA polymerase III, delta prime subunit |
885 | 1002 | COG0496 | L | Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE |
1079 | 1120 | COG0497 | L | DNA repair ATPase RecN |
877 | 1445 | COG0507 | L | ATPase/5’-3’ helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) |
1170 | 3707 | COG0513 | L | Superfamily II DNA and RNA helicase |
924 | 1572 | COG0514 | L | Superfamily II DNA helicase RecQ |
1168 | 1168 | COG0536 | L D | GTPase involved in cell partioning and DNA repair |
1276 | 1859 | COG0550 | L | DNA topoisomerase IA |
658 | 933 | COG0551 | L | DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains |
856 | 1713 | COG0553 | K L | Superfamily II DNA or RNA helicase, SNF2 family |
1204 | 1220 | COG0556 | L | Excinuclease UvrABC helicase subunit UvrB |
445 | 976 | COG0582 | L X | Integrase/recombinase, includes phage integrase |
1174 | 1827 | COG0587 | L | DNA polymerase III, alpha subunit |
1297 | 1474 | COG0592 | L | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog |
1151 | 1733 | COG0593 | L | Chromosomal replication initiation ATPase DnaA |
1093 | 1249 | COG0608 | L | ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation |
1176 | 2146 | COG0629 | L | Single-stranded DNA-binding protein |
1151 | 1148 | COG0632 | L | Holliday junction resolvasome RuvABC DNA-binding subunit |
595 | 653 | COG0648 | L | Endonuclease IV |
740 | 759 | COG0692 | L | Uracil-DNA glycosylase |
8 | 9 | COG0699 | L | Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) |
1063 | 1683 | COG0708 | L | Exonuclease III |
1131 | 1323 | COG0749 | L | DNA polymerase I, 3'-5' exonuclease and polymerase domains |
1114 | 1264 | COG0758 | L | Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake |
1143 | 3043 | COG0776 | L | Bacterial nucleoid DNA-binding protein IHF-alpha |
1033 | 1043 | COG0792 | L | Predicted endonuclease distantly related to archaeal Holliday junction resolvase, YraN/UPF0102 family |
1129 | 1175 | COG0816 | J K L | YqgF/RuvX protein, pre-16S rRNA maturation RNase/Holliday junction resolvase/anti-termination factor |
1055 | 1086 | COG0817 | L | Holliday junction resolvasome RuvABC endonuclease subunit RuvC |
115 | 126 | COG0827 | L | Adenine-specific DNA N6-methylase |
951 | 1998 | COG0847 | L | DNA polymerase III, epsilon subunit or related 3'-5' exonuclease |
646 | 1285 | COG0863 | L | DNA modification methylase |
108 | 110 | COG1039 | L | Ribonuclease HIII |
862 | 925 | COG1058 | L | ADP-ribose pyrophosphatase domain of DNA damage- and competence-inducible protein CinA |
60 | 60 | COG1059 | L V | Thermostable 8-oxoguanine DNA glycosylase |
821 | 1608 | COG1061 | K L | Superfamily II DNA or RNA helicase |
1075 | 1103 | COG1066 | L | DNA repair protein RadA/Sms, contains AAA+ ATPase domain |
1017 | 1185 | COG1074 | L | 3’-5’ helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) |
72 | 103 | COG1107 | L | Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain |
64 | 84 | COG1110 | L | Reverse gyrase |
136 | 136 | COG1111 | L | ERCC4-related helicase |
557 | 840 | COG1112 | L | Superfamily I DNA and/or RNA helicase |
529 | 617 | COG1193 | L | dsDNA-specific endonuclease/ATPase MutS2 |
1009 | 1034 | COG1194 | L | Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs |
965 | 1005 | COG1195 | L | Recombinational DNA repair ATPase RecF |
1115 | 1135 | COG1197 | K L | Transcription-repair coupling factor (superfamily II helicase) |
1139 | 1150 | COG1198 | L | Primosomal protein N' (replication factor Y) - superfamily II helicase |
864 | 1189 | COG1199 | L | Rad3-related DNA helicase DinG |
1083 | 1110 | COG1200 | L | RecG-like helicase |
562 | 754 | COG1201 | L | Lhr-like helicase |
68 | 107 | COG1202 | L | Superfamily II helicase, archaea-specific |
270 | 338 | COG1204 | L | Replicative superfamily II helicase |
452 | 598 | COG1205 | L | ATP-dependent helicase YprA, contains C-terminal metal-binding DUF1998 domain |
120 | 164 | COG1241 | L | DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family |
319 | 407 | COG1273 | L | Non-homologous end joining protein Ku, dsDNA break repair |
96 | 96 | COG1311 | L | Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B |
787 | 803 | COG1322 | L | DNA anti-recombination protein (rearrangement mutator) RmuC |
304 | 309 | COG1330 | L | Scaffold subunit RecC of the DNA repair enzyme RecBCD (exonuclease V) |
946 | 953 | COG1354 | L | Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family |
177 | 330 | COG1372 | L X | Intein/homing endonuclease |
1093 | 1093 | COG1381 | L | Recombinational DNA repair protein RecO (RecF pathway) |
126 | 128 | COG1389 | L | DNA topoisomerase VI, subunit B |
71 | 71 | COG1423 | L | ATP-dependent RNA circularization protein, DNA/RNA ligase (PAB1020) family |
1150 | 1168 | COG1466 | L | DNA polymerase III, delta subunit |
119 | 124 | COG1467 | L | Eukaryotic-type DNA primase, catalytic (small) subunit |
197 | 593 | COG1474 | L | Cdc6-related protein, AAA superfamily ATPase |
575 | 1496 | COG1484 | L | DNA replication protein DnaC |
364 | 375 | COG1515 | L | Deoxyinosine 3'-endonuclease (endonuclease V) |
598 | 1003 | COG1525 | L | Endonuclease YncB, thermonuclease family |
627 | 815 | COG1533 | L | DNA repair photolyase |
881 | 1051 | COG1555 | L | DNA uptake protein ComE or related DNA-binding protein |
1035 | 1053 | COG1570 | L | Exonuclease VII, large subunit |
905 | 1545 | COG1573 | L | Uracil-DNA glycosylase |
93 | 101 | COG1591 | L | Holliday junction resolvase Hjc, archaeal type |
116 | 239 | COG1599 | L | ssDNA-binding replication factor A, large subunit |
117 | 132 | COG1602 | L | Archaeal DNA repair protein NreA |
39 | 40 | COG1630 | L | ssDNA and dsDNA 5'-3' nuclease NurA, repair of double-stranded DNA breaks |
265 | 309 | COG1637 | L | Endonuclease NucS, RecB family |
136 | 139 | COG1697 | L | DNA topoisomerase VI, subunit A |
85 | 87 | COG1711 | L | DNA replication initiation complex subunit, GINS family |
984 | 986 | COG1722 | L | Exonuclease VII small subunit |
173 | 223 | COG1743 | L | Adenine-specific DNA methylase, contains a Zn-ribbon domain |
627 | 1117 | COG1793 | L | ATP-dependent DNA ligase |
324 | 352 | COG1796 | L | DNA polymerase/3'-5' exonuclease PolX |
84 | 84 | COG1860 | L F | Predicted metal-binding protein, contains two cysteine clusters, UPF0179 family |
95 | 95 | COG1933 | L | Archaeal DNA polymerase II, large subunit |
133 | 149 | COG1948 | L | ERCC4-type crossover junction endonuclease |
797 | 2599 | COG1961 | L | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE |
917 | 1281 | COG2003 | L | DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif |
426 | 429 | COG2094 | L | 3-methyladenine DNA glycosylase Mpg |
611 | 836 | COG2135 | L | ssDNA abasic site-binding protein YedK/HMCES, SRAP family |
493 | 606 | COG2169 | L | Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains |
545 | 763 | COG2176 | L | DNA polymerase III, alpha subunit (gram-positive type) |
363 | 486 | COG2189 | L | Adenine specific DNA methylase Mod |
117 | 122 | COG2219 | L | Eukaryotic-type DNA primase, large subunit |
173 | 173 | COG2231 | L | 3-Methyladenine DNA glycosylase, HhH-GPD/Endo3 superfamily |
1142 | 1161 | COG2255 | L | Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB |
1105 | 1163 | COG2256 | L | Replication-associated recombination protein RarA (DNA-dependent ATPase) |
345 | 346 | COG2354 | L | Membrane protein MutK/YedI, may be involved in DNA repair |
231 | 309 | COG2356 | L | Endonuclease I |
90 | 109 | COG2406 | L | Ferritin-like DNA-binding protein, DPS (DNA Protection under Starvation) family |
1186 | 1795 | COG2812 | L | DNA polymerase III, gamma/tau subunits |
699 | 810 | COG2818 | L | 3-methyladenine DNA glycosylase Tag |
623 | 1007 | COG2827 | L | Predicted endonuclease, GIY-YIG superfamily |
495 | 563 | COG2840 | L | DNA-nicking endonuclease, Smr domain |
403 | 719 | COG2852 | L | Very-short-patch-repair endonuclease |
479 | 668 | COG2887 | L | RecB family exonuclease |
253 | 257 | COG2925 | L | Exonuclease I (degrades ssDNA) |
460 | 460 | COG2927 | L | DNA polymerase III, chi subunit |
44 | 61 | COG2946 | L | DNA relaxase NicK |
193 | 191 | COG2965 | L | Primosomal replication protein N |
267 | 299 | COG2974 | L | DNA recombination-dependent growth factor RdgC |
546 | 550 | COG3022 | L | DNA-binding protein YaaA associated with the oxidative stress response |
436 | 437 | COG3024 | L | Endogenous inhibitor of DNA gyrase, YacG/DUF329 family |
85 | 85 | COG3050 | L | DNA polymerase III, psi subunit |
96 | 97 | COG3057 | L | Negative regulator of replication initiation SeqA |
126 | 126 | COG3066 | L | DNA mismatch repair protein MutH |
136 | 144 | COG3081 | L | dsDNA-binding nucleoid-associated protein YejK/NdpA |
74 | 75 | COG3120 | L | Macrodomain Ter protein organizer, MatP/YcbG family |
89 | 91 | COG3141 | L | dsDNA-binding SOS-regulon protein YebG, induction by DNA damage requires cAMP |
455 | 526 | COG3145 | L | Alkylated DNA repair dioxygenase AlkB |
304 | 331 | COG3214 | L | DNA glycosylase YcaQ, repair of DNA interstrand crosslinks |
330 | 554 | COG3285 | L | Eukaryotic-type DNA primase |
89 | 89 | COG3298 | L | Predicted 3'-5' exonuclease related to the exonuclease domain of PolB |
72 | 124 | COG3390 | L | Replication protein A (RPA) family protein |
93 | 103 | COG3392 | L | Adenine-specific DNA methylase |
233 | 301 | COG3449 | L | DNA gyrase inhibitor GyrI/SbmC |
241 | 246 | COG3569 | L | DNA topoisomerase IB |
476 | 650 | COG3593 | L | Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains |
183 | 238 | COG3598 | L | RecA-family ATPase |
85 | 86 | COG3611 | L | Replication initiation and membrane attachment protein DnaB |
402 | 415 | COG3663 | L | G:T/U-mismatch repair DNA glycosylase |
76 | 87 | COG3723 | L | Recombinational DNA repair protein RecT |
303 | 345 | COG3727 | L | G:T-mismatch repair DNA endonuclease Vsr, very short patch repair protein |
213 | 384 | COG3743 | L | Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain |
8 | 10 | COG3780 | L | DNA endonuclease related to intein-encoded endonucleases |
385 | 398 | COG3857 | L | ATP-dependent helicase/DNAse subunit B |
182 | 200 | COG3886 | L | HKD family nuclease |
311 | 313 | COG3893 | L | Inactivated superfamily I helicase |
75 | 75 | COG3923 | L | Primosomal replication protein N'' |
172 | 256 | COG3935 | L | DNA replication protein DnaD |
90 | 97 | COG3972 | L | Superfamily I DNA and RNA helicases |
256 | 421 | COG3973 | L | DNA helicase IV |
35 | 35 | COG4047 | L | N-glycosylase/DNA lyase (8-oxoguanine DNA glycosylase) |
90 | 91 | COG4098 | L | Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) |
71 | 71 | COG4199 | L | ssDNA-specific exonuclease RecJ |
207 | 383 | COG4227 | L | Antirestriction protein ArdC |
103 | 109 | COG4294 | L | UV DNA damage repair endonuclease |
177 | 189 | COG4335 | L | 3-methylpurine DNA glycosylase AlkC |
94 | 98 | COG4389 | L | Site-specific recombinase |
95 | 97 | COG4467 | L | Regulator of replication initiation timing YabA |
145 | 181 | COG4570 | L | Holliday junction resolvase RusA (prophage-encoded endonuclease) |
383 | 542 | COG4581 | L | Superfamily II RNA helicase |
105 | 132 | COG4646 | L | Adenine-specific DNA methylase, N12 class |
33 | 41 | COG4712 | L | Predicted ssDNA annealing protein, contains HHH motif, Rad42/Rad22/RecT/erf family |
52 | 76 | COG4817 | L | DNA-binding ferritin-like protein (Dps family) |
357 | 438 | COG4912 | L | 3-methyladenine DNA glycosylase AlkD |
459 | 618 | COG4973 | L | Site-specific recombinase XerC |
1246 | 7290 | COG4974 | L | Site-specific recombinase XerD |
17 | 17 | COG4998 | L | Predicted endonuclease, RecB family |
5 | 5 | COG5055 | L | Recombinational DNA repair protein (RAD52 pathway) |
146 | 673 | COG5464 | L | Recombination-promoting DNA endonuclease RpnC/YadD |
28 | 35 | COG5851 | L D | Stage 0 sporulation inhibitor Sda, checkpoint for initiation of sporulation and replication |