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L - Replication, recombination and repair

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COG
definitions
Organims Proteins Median Protein
Length
Genes
189 1,309 146,012 380.0 169
Organism Protein COG Cat Annotation
735 1018 COG0122 L 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
1233 1247 COG0164 L Ribonuclease HII
1230 1458 COG0177 L Endonuclease III
1216 1870 COG0178 L Excinuclease UvrABC ATPase subunit
1243 2111 COG0187 L DNA gyrase/topoisomerase IV, subunit B
1247 2132 COG0188 L DNA gyrase/topoisomerase IV, subunit A
1227 2976 COG0210 L Superfamily I DNA or RNA helicase
1019 1349 COG0249 L DNA mismatch repair ATPase MutS
1284 1578 COG0258 L 5'-3' exonuclease Xni/ExoIX (flap endonuclease)
924 1395 COG0266 L Formamidopyrimidine-DNA glycosylase
648 1271 COG0270 L DNA-cytosine methylase
1187 1391 COG0272 L NAD-dependent DNA ligase
1181 1530 COG0305 L Replicative DNA helicase
1202 1553 COG0322 L Excinuclease UvrABC, nuclease subunit
1018 1102 COG0323 L DNA mismatch repair ATPase MutL
1082 1292 COG0328 L Ribonuclease HI
478 713 COG0338 L DNA-adenine methylase
1159 1729 COG0350 L DNA repair enzyme Ada (O6-methylguanine-DNA--protein-cysteine methyltransferase)
1128 1126 COG0353 L Recombinational DNA repair protein RecR
1290 1731 COG0358 L DNA primase (bacterial type)
1056 2020 COG0389 L Nucleotidyltransferase/DNA polymerase DinP involved in DNA repair
779 1071 COG0415 L Deoxyribodipyrimidine photolyase
318 419 COG0417 L DNA polymerase B elongation subunit
856 1249 COG0419 L DNA repair exonuclease SbcCD ATPase subunit
888 1179 COG0420 L DNA repair exonuclease SbcCD nuclease subunit
811 1373 COG0433 L Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains
1278 1463 COG0468 L RecA/RadA recombinase
700 819 COG0470 L DNA polymerase III, delta prime subunit
885 1002 COG0496 L Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE
1079 1120 COG0497 L DNA repair ATPase RecN
877 1445 COG0507 L ATPase/5’-3’ helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V)
1170 3707 COG0513 L Superfamily II DNA and RNA helicase
924 1572 COG0514 L Superfamily II DNA helicase RecQ
1168 1168 COG0536 L D GTPase involved in cell partioning and DNA repair
1276 1859 COG0550 L DNA topoisomerase IA
658 933 COG0551 L DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains
856 1713 COG0553 K L Superfamily II DNA or RNA helicase, SNF2 family
1204 1220 COG0556 L Excinuclease UvrABC helicase subunit UvrB
445 976 COG0582 L X Integrase/recombinase, includes phage integrase
1174 1827 COG0587 L DNA polymerase III, alpha subunit
1297 1474 COG0592 L DNA polymerase III sliding clamp (beta) subunit, PCNA homolog
1151 1733 COG0593 L Chromosomal replication initiation ATPase DnaA
1093 1249 COG0608 L ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation
1176 2146 COG0629 L Single-stranded DNA-binding protein
1151 1148 COG0632 L Holliday junction resolvasome RuvABC DNA-binding subunit
595 653 COG0648 L Endonuclease IV
740 759 COG0692 L Uracil-DNA glycosylase
8 9 COG0699 L Replication fork clamp-binding protein CrfC (dynamin-like GTPase family)
1063 1683 COG0708 L Exonuclease III
1131 1323 COG0749 L DNA polymerase I, 3'-5' exonuclease and polymerase domains
1114 1264 COG0758 L Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake
1143 3043 COG0776 L Bacterial nucleoid DNA-binding protein IHF-alpha
1033 1043 COG0792 L Predicted endonuclease distantly related to archaeal Holliday junction resolvase, YraN/UPF0102 family
1129 1175 COG0816 J K L YqgF/RuvX protein, pre-16S rRNA maturation RNase/Holliday junction resolvase/anti-termination factor
1055 1086 COG0817 L Holliday junction resolvasome RuvABC endonuclease subunit RuvC
115 126 COG0827 L Adenine-specific DNA N6-methylase
951 1998 COG0847 L DNA polymerase III, epsilon subunit or related 3'-5' exonuclease
646 1285 COG0863 L DNA modification methylase
108 110 COG1039 L Ribonuclease HIII
862 925 COG1058 L ADP-ribose pyrophosphatase domain of DNA damage- and competence-inducible protein CinA
60 60 COG1059 L V Thermostable 8-oxoguanine DNA glycosylase
821 1608 COG1061 K L Superfamily II DNA or RNA helicase
1075 1103 COG1066 L DNA repair protein RadA/Sms, contains AAA+ ATPase domain
1017 1185 COG1074 L 3’-5’ helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V)
72 103 COG1107 L Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain
64 84 COG1110 L Reverse gyrase
136 136 COG1111 L ERCC4-related helicase
557 840 COG1112 L Superfamily I DNA and/or RNA helicase
529 617 COG1193 L dsDNA-specific endonuclease/ATPase MutS2
1009 1034 COG1194 L Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs
965 1005 COG1195 L Recombinational DNA repair ATPase RecF
1115 1135 COG1197 K L Transcription-repair coupling factor (superfamily II helicase)
1139 1150 COG1198 L Primosomal protein N' (replication factor Y) - superfamily II helicase
864 1189 COG1199 L Rad3-related DNA helicase DinG
1083 1110 COG1200 L RecG-like helicase
562 754 COG1201 L Lhr-like helicase
68 107 COG1202 L Superfamily II helicase, archaea-specific
270 338 COG1204 L Replicative superfamily II helicase
452 598 COG1205 L ATP-dependent helicase YprA, contains C-terminal metal-binding DUF1998 domain
120 164 COG1241 L DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family
319 407 COG1273 L Non-homologous end joining protein Ku, dsDNA break repair
96 96 COG1311 L Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B
787 803 COG1322 L DNA anti-recombination protein (rearrangement mutator) RmuC
304 309 COG1330 L Scaffold subunit RecC of the DNA repair enzyme RecBCD (exonuclease V)
946 953 COG1354 L Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family
177 330 COG1372 L X Intein/homing endonuclease
1093 1093 COG1381 L Recombinational DNA repair protein RecO (RecF pathway)
126 128 COG1389 L DNA topoisomerase VI, subunit B
71 71 COG1423 L ATP-dependent RNA circularization protein, DNA/RNA ligase (PAB1020) family
1150 1168 COG1466 L DNA polymerase III, delta subunit
119 124 COG1467 L Eukaryotic-type DNA primase, catalytic (small) subunit
197 593 COG1474 L Cdc6-related protein, AAA superfamily ATPase
575 1496 COG1484 L DNA replication protein DnaC
364 375 COG1515 L Deoxyinosine 3'-endonuclease (endonuclease V)
598 1003 COG1525 L Endonuclease YncB, thermonuclease family
627 815 COG1533 L DNA repair photolyase
881 1051 COG1555 L DNA uptake protein ComE or related DNA-binding protein
1035 1053 COG1570 L Exonuclease VII, large subunit
905 1545 COG1573 L Uracil-DNA glycosylase
93 101 COG1591 L Holliday junction resolvase Hjc, archaeal type
116 239 COG1599 L ssDNA-binding replication factor A, large subunit
117 132 COG1602 L Archaeal DNA repair protein NreA
39 40 COG1630 L ssDNA and dsDNA 5'-3' nuclease NurA, repair of double-stranded DNA breaks
265 309 COG1637 L Endonuclease NucS, RecB family
136 139 COG1697 L DNA topoisomerase VI, subunit A
85 87 COG1711 L DNA replication initiation complex subunit, GINS family
984 986 COG1722 L Exonuclease VII small subunit
173 223 COG1743 L Adenine-specific DNA methylase, contains a Zn-ribbon domain
627 1117 COG1793 L ATP-dependent DNA ligase
324 352 COG1796 L DNA polymerase/3'-5' exonuclease PolX
84 84 COG1860 L F Predicted metal-binding protein, contains two cysteine clusters, UPF0179 family
95 95 COG1933 L Archaeal DNA polymerase II, large subunit
133 149 COG1948 L ERCC4-type crossover junction endonuclease
797 2599 COG1961 L Site-specific DNA recombinase SpoIVCA/DNA invertase PinE
917 1281 COG2003 L DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif
426 429 COG2094 L 3-methyladenine DNA glycosylase Mpg
611 836 COG2135 L ssDNA abasic site-binding protein YedK/HMCES, SRAP family
493 606 COG2169 L Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains
545 763 COG2176 L DNA polymerase III, alpha subunit (gram-positive type)
363 486 COG2189 L Adenine specific DNA methylase Mod
117 122 COG2219 L Eukaryotic-type DNA primase, large subunit
173 173 COG2231 L 3-Methyladenine DNA glycosylase, HhH-GPD/Endo3 superfamily
1142 1161 COG2255 L Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB
1105 1163 COG2256 L Replication-associated recombination protein RarA (DNA-dependent ATPase)
345 346 COG2354 L Membrane protein MutK/YedI, may be involved in DNA repair
231 309 COG2356 L Endonuclease I
90 109 COG2406 L Ferritin-like DNA-binding protein, DPS (DNA Protection under Starvation) family
1186 1795 COG2812 L DNA polymerase III, gamma/tau subunits
699 810 COG2818 L 3-methyladenine DNA glycosylase Tag
623 1007 COG2827 L Predicted endonuclease, GIY-YIG superfamily
495 563 COG2840 L DNA-nicking endonuclease, Smr domain
403 719 COG2852 L Very-short-patch-repair endonuclease
479 668 COG2887 L RecB family exonuclease
253 257 COG2925 L Exonuclease I (degrades ssDNA)
460 460 COG2927 L DNA polymerase III, chi subunit
44 61 COG2946 L DNA relaxase NicK
193 191 COG2965 L Primosomal replication protein N
267 299 COG2974 L DNA recombination-dependent growth factor RdgC
546 550 COG3022 L DNA-binding protein YaaA associated with the oxidative stress response
436 437 COG3024 L Endogenous inhibitor of DNA gyrase, YacG/DUF329 family
85 85 COG3050 L DNA polymerase III, psi subunit
96 97 COG3057 L Negative regulator of replication initiation SeqA
126 126 COG3066 L DNA mismatch repair protein MutH
136 144 COG3081 L dsDNA-binding nucleoid-associated protein YejK/NdpA
74 75 COG3120 L Macrodomain Ter protein organizer, MatP/YcbG family
89 91 COG3141 L dsDNA-binding SOS-regulon protein YebG, induction by DNA damage requires cAMP
455 526 COG3145 L Alkylated DNA repair dioxygenase AlkB
304 331 COG3214 L DNA glycosylase YcaQ, repair of DNA interstrand crosslinks
330 554 COG3285 L Eukaryotic-type DNA primase
89 89 COG3298 L Predicted 3'-5' exonuclease related to the exonuclease domain of PolB
72 124 COG3390 L Replication protein A (RPA) family protein
93 103 COG3392 L Adenine-specific DNA methylase
233 301 COG3449 L DNA gyrase inhibitor GyrI/SbmC
241 246 COG3569 L DNA topoisomerase IB
476 650 COG3593 L Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains
183 238 COG3598 L RecA-family ATPase
85 86 COG3611 L Replication initiation and membrane attachment protein DnaB
402 415 COG3663 L G:T/U-mismatch repair DNA glycosylase
76 87 COG3723 L Recombinational DNA repair protein RecT
303 345 COG3727 L G:T-mismatch repair DNA endonuclease Vsr, very short patch repair protein
213 384 COG3743 L Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain
8 10 COG3780 L DNA endonuclease related to intein-encoded endonucleases
385 398 COG3857 L ATP-dependent helicase/DNAse subunit B
182 200 COG3886 L HKD family nuclease
311 313 COG3893 L Inactivated superfamily I helicase
75 75 COG3923 L Primosomal replication protein N''
172 256 COG3935 L DNA replication protein DnaD
90 97 COG3972 L Superfamily I DNA and RNA helicases
256 421 COG3973 L DNA helicase IV
35 35 COG4047 L N-glycosylase/DNA lyase (8-oxoguanine DNA glycosylase)
90 91 COG4098 L Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)
71 71 COG4199 L ssDNA-specific exonuclease RecJ
207 383 COG4227 L Antirestriction protein ArdC
103 109 COG4294 L UV DNA damage repair endonuclease
177 189 COG4335 L 3-methylpurine DNA glycosylase AlkC
94 98 COG4389 L Site-specific recombinase
95 97 COG4467 L Regulator of replication initiation timing YabA
145 181 COG4570 L Holliday junction resolvase RusA (prophage-encoded endonuclease)
383 542 COG4581 L Superfamily II RNA helicase
105 132 COG4646 L Adenine-specific DNA methylase, N12 class
33 41 COG4712 L Predicted ssDNA annealing protein, contains HHH motif, Rad42/Rad22/RecT/erf family
52 76 COG4817 L DNA-binding ferritin-like protein (Dps family)
357 438 COG4912 L 3-methyladenine DNA glycosylase AlkD
459 618 COG4973 L Site-specific recombinase XerC
1246 7290 COG4974 L Site-specific recombinase XerD
17 17 COG4998 L Predicted endonuclease, RecB family
5 5 COG5055 L Recombinational DNA repair protein (RAD52 pathway)
146 673 COG5464 L Recombination-promoting DNA endonuclease RpnC/YadD
28 35 COG5851 L D Stage 0 sporulation inhibitor Sda, checkpoint for initiation of sporulation and replication