Retrieve studies that investigate the effect of smoking or diet on non-human mammals
(smok* OR diet) AND (mammals[organism] NOT human[organism])
Search for studies that examine gene expression using next-generation sequencing
"expression profiling by high throughput sequencing"[DataSet Type]
Retrieve submissions that have Affymetrix CEL files
cel[Supplementary Files]
Search for curated DataSets that have 'age' as an experimental variable
age[Subset Variable Type]
Retrieve studies that consist of between 100 and 500 samples
100:500[Number of Samples]
Retrieve studies that include ‘Smith, A.’ as an author
smith a[Author]

From: Gene Expression Omnibus (GEO)

Cover of The NCBI Handbook
The NCBI Handbook [Internet]. 2nd edition.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.