A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors can be identified. This entry corresponds to the RNA isolated from tet-induced INS-1 cell line #6a containing MODY5 mutant P328L329delCCTCT of hepatocyte nuclear factor-1b (HNF1b). Keywords = INS-1 Keywords = beta-cell Keywords = HNF1b Keywords = P328L329 Keywords = MODY5 Keywords = tetracycline Keywords = FRT
