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| Status |
Public on Sep 13, 2017 |
| Title |
Identification of mRNAs modulated by the HOXB7-MEK signaling cascade |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Transcripts upregulated or downregulated by HOXB7-MEK signaling were identified for use on the microarray using the Affymetrix GeneChip WT PLUS Reagent Kit in comparison with HOXB7-knockdown S2-013 cells that were transfected with rescue-HOXB7 plasmid and treated with MEK inhibitor, and HOXB7-knockdown S2-013 cells that were transfected with rescue-HOXB7 plasmid but not treated with MEK inhibitor.
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| Overall design |
We endeavored to identify factors and pathways regulated by HOXB7-MEK signaling and to obtain leads regarding the mechanism underpinning the observed phenotypic changes by performing cDNA microarray analysis.
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| Contributor(s) |
Taniuchi K |
| Citation(s) |
28912272 |
| Submission date |
Apr 19, 2017 |
| Last update date |
Mar 15, 2019 |
| Contact name |
Keisuke Taniuchi |
| E-mail(s) |
ktaniuchi@kochi-u.ac.jp
|
| Organization name |
Kochi Medical School
|
| Street address |
Kohasu
|
| City |
Nankoku |
| ZIP/Postal code |
783-8505 |
| Country |
Japan |
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| Platforms (1) |
| GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (2) |
| GSM2584460 |
HOXB7-knockdown S2-013 cells transfected with rescue-HOXB7 plasmid and treated with MEK inhibitor |
| GSM2584461 |
Control (HOXB7-knockdown S2-013 cells transfected with rescue-HOXB7 plasmid but not treated with MEK inhibitor) |
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| Relations |
| BioProject |
PRJNA383539 |
