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| Status |
Public on Apr 28, 2017 |
| Title |
Characterization by gene expression arrays of the human CRC populations according to the Ki67 and Lgr5 expression levels |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
In normal intestine, Lgr5 are a pool of rapidly dividing stem cells that gives rise to the whole intestinal crypts. Here we have labelled both Lgr5 and Ki67 genes with fluorescent markers by means of CRISPR/Cas9 in human patient derived organoids (PDO).
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| Overall design |
Total RNA was collected from Lgr+Ki67+, Lgr5+Ki67-, Lgr5-Ki67+ and Lgr5-Ki67- populations sorted by FACS
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| Contributor(s) |
Stephan-Otto Attolini C, Cortina C, Turon G |
| Citation(s) |
28468934 |
| Submission date |
Dec 28, 2016 |
| Last update date |
Aug 23, 2018 |
| Contact name |
Camille Stephan Otto Attolini |
| Organization name |
IRB Barcelona
|
| Department |
Biostatistics and bioinformatics Unit
|
| Street address |
Baldiri Reixac 10
|
| City |
Barcelona |
| State/province |
Select a State or Province |
| ZIP/Postal code |
08028 |
| Country |
Spain |
| |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (16)
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| This SubSeries is part of SuperSeries: |
| GSE92962 |
A genome editing approach to study cancer stem cells in human tumors |
|
| Relations |
| BioProject |
PRJNA359321 |
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