|
| Status |
Public on Mar 31, 2017 |
| Title |
Molecular reprogramming of granulocyte/macrophage progenitor (GMP) clusters upon induction of BCR/ABL oncogene |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Single cell RNA Seq and bioinformatic analysis are used to study what processes are important for the molecular reprogramming of GMPs once mice develop chronic myelogenous leukemia-like (CML-like) myeloproliferative neoplasm (MPN) upon induction of BCR/ABL oncogene.
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| |
|
| Overall design |
Single cell RNA sequencing of GMP cells from mice upon induction of BCR/ABL oncogene
|
| |
|
| Contributor(s) |
Hérault A, Binnewies M, Leong S, Calero-Nieto FJ, Zhang SY, Kang Y, Wang X, Pietras EM, Chu SH, Barry-Holson K, Armstrong S, Göttgens B, Passegué E |
| Citation(s) |
28355185 |
| Submission date |
Dec 02, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Evangelia Diamanti |
| E-mail(s) |
ed347@cam.ac.uk
|
| Phone |
01223 62317
|
| Organization name |
University of Cambridge
|
| Department |
Haematology
|
| Lab |
Gottgens
|
| Street address |
Wellcome Trust / MRC Building, Hills Road
|
| City |
Cambridge |
| ZIP/Postal code |
CB2 0XY |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (384)
|
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| This SubSeries is part of SuperSeries: |
| GSE90799 |
Molecular reprogramming of granulocyte/macrophage progenitor (GMP) clusters |
|
| Relations |
| BioProject |
PRJNA355981 |
| SRA |
SRP094466 |
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