|
| Status |
Public on Mar 05, 2008 |
| Title |
NIK/NF-kappaB2 regulated gene products. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
This study aims at identifying genes that are NIK/NF-kappaB2 responsive in murine dendritic cells matured in vivo.
Keywords: NIK/NF-kappaB2 responsive genes in dendritic cells after TLR/CD40 signaling
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| |
|
| Overall design |
This study isolated dendritic cells from the spleens of Alymphoplasia or heterozygeous littlermates (wild type). Mice were eiter not treated as a reference or treated I.P. with 25 micrograms of LPS and 100 micrograms of agonistic anti-CD40 antibody. DCs were isolated 6 hours after treatment allowing in vivo maturation via both TLR and CD40 signals. DCs from 3 mice per group were pooled. Experiment was performed in triplicate.
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| |
|
| Contributor(s) |
Lind EF, Noelle RJ |
| Citation(s) |
18566401 |
| Submission date |
Mar 07, 2007 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Evan F. Lind |
| E-mail(s) |
linde@ohsu.edu
|
| Phone |
503 494-1347
|
| Organization name |
Oregon Health & Science University
|
| Department |
Molecular Microbiology and Immunology
|
| Street address |
Mail Code L220, 3181 SW Sam Jackson Park Road
|
| City |
Portland |
| State/province |
OR |
| ZIP/Postal code |
97239 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
|
| Samples (12)
|
| GSM173580 |
WT Dendritic Cells_untreated_replicate1 |
| GSM173581 |
WT Dendritic Cells_untreated_replicate2 |
| GSM173582 |
WT Dendritic Cells_untreated_replicate3 |
| GSM173584 |
Alymphoplasia splenic DC ex-vivo from untreated replicate 1 |
| GSM173585 |
Alymphoplasia splenic DC ex-vivo from untreated replicate 2 |
| GSM173586 |
Alymphoplasia splenic DC ex-vivo from untreated replicate 3 |
| GSM173588 |
WT Dendritic Cells_LPS+anti-CD40_replicate1 |
| GSM173590 |
WT Dendritic Cells_LPS+anti-CD40_replicate2 |
| GSM173591 |
WT Dendritic Cells_LPS+anti-CD40_replicate3 |
| GSM173592 |
Alymphoplasia Dendritic Cells_LPS+anti-CD40_replicate1 |
| GSM173593 |
Alymphoplasia Dendritic Cells_LPS+anti-CD40_replicate2 |
| GSM173594 |
Alymphoplasia Dendritic Cells_LPS+anti-CD40_replicate3 |
|
| Relations |
| BioProject |
PRJNA98289 |
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