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| Status |
Public on Mar 08, 2007 |
| Title |
Differential gene expression between WT and ERRa-null hearts |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Total RNA was isolated from 3 WT and 3 ERRa null hearts and independent hybridizations were performed using MOE430 2.0 microarrays. Expression profiling was conducted to determine changes in gene expression in hearts lacking ERRa. The expression of genes involved in heart and muscle development, muscle contraction, lipid metabolism, OxPhos, protein metabolism and transcription were affected by the loss of ERRa.
Keywords: microarray and genetic modification
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| |
|
| Overall design |
3 hearts from WT and 3 hearts from ERRa-null mice were used in the study. The expression of genes in the ERRa KO hearts were compared to the reference WT hearts.
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| |
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| Contributor(s) |
Dufour CR, Wilson BJ, Giguère V |
| Citation(s) |
17488637 |
| Submission date |
Mar 05, 2007 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Vincent Giguère |
| E-mail(s) |
vincent.giguere@mcgill.ca
|
| Phone |
514-398-5899
|
| Organization name |
McGill University
|
| Department |
Goodman Cancer Centre
|
| Street address |
1160 Pine Ave West, McIntyre Bldg Room 710
|
| City |
Montréal |
| State/province |
QC |
| ZIP/Postal code |
H3A 1A3 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
|
| Samples (6)
|
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| Relations |
| BioProject |
PRJNA98241 |
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