|
Status |
Public on Sep 28, 2016 |
Title |
Gene Expression data from synovium in mouse serum transfer arthritis model (STA) model |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
|
Summary |
To find regulated genes during peak inflammation of rheumatoid arthritis (RA), we have collected synovium from mouse Serum Transfer Arthtitis (STA) model at day 0 (Non Arthritic) and day 10 (Peak Inflammation). Serum transfer arthritis was induced in 12-week-old male C57BL/6J mice (The Jackson Laboratory) by intraperitoneal injection of 150 μl of arthritogenic serum on days 0, 2, and 7. Nonarthritic mice received 150 μl of sterile phosphate buffered saline at each time point.
|
|
|
Overall design |
We analyzed gene expression data from Non-arthritic synovium pooled from 3 mice and Arthritic synovium at peak inflammation pooled from 10 mice. Two biological replicates for each time points.
|
|
|
Contributor(s) |
Maeda Y, Farina NH, Matzelle M, Fanning PJ, Lian JB, Gravallese1 EM |
Citation(s) |
27676131 |
Submission date |
Jul 31, 2015 |
Last update date |
Feb 21, 2018 |
Contact name |
yukiko maeda |
E-mail(s) |
yukiko.maeda@umassmed.edu
|
Phone |
508 856 6357
|
Organization name |
Umass Medical School
|
Department |
Medicine
|
Lab |
Gravallese
|
Street address |
364 Plantation Street
|
City |
worcester |
State/province |
massachusetts |
ZIP/Postal code |
01605 |
Country |
USA |
|
|
Platforms (1) |
GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
|
Samples (4)
|
|
This SubSeries is part of SuperSeries: |
GSE71601 |
Gene and miRNA Expression data from synovium in mouse serum transfer arthritis model (STA) model |
|
Relations |
BioProject |
PRJNA291602 |