|
| Status |
Public on Nov 25, 2015 |
| Title |
Dexamethasone treatment alters levels of insulin, leptin, and adiponectin but does not have metabolic effects across generations |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Genome-wide expression analysis of sperms did not identify significant transcriptome changes upon dexamethasone treatment in mice. These results are consistent with the observation that dexamethasone treatment of parental male mice did not induce metabolic changes in the F1 generation.
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| |
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| Overall design |
We performed gene expression microarray analysis of sperms derived from dexamethasone-treated (n=8) or control mice (n=7).
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| Contributor(s) |
Bönisch C, Huypens P, Irmler M, Brachthäuser L, Neff F, Marschall S, HrabédeAngelis M, Beckers J |
| Citation(s) |
26662513 |
| Submission date |
Mar 25, 2015 |
| Last update date |
Feb 21, 2018 |
| Contact name |
Johannes Beckers |
| E-mail(s) |
johannes.beckers@helmholtz-munich.de
|
| Organization name |
Helmholtz Zentrum Muenchen
|
| Department |
Institute of Experimental Genetics
|
| Street address |
Ingolstaedter Landstr. 1
|
| City |
Neuherberg |
| ZIP/Postal code |
85764 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (15)
|
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| Relations |
| BioProject |
PRJNA279415 |
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