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| Status |
Public on Jan 09, 2008 |
| Title |
Perirenal and epididymal preadipocytes from young and old rats. |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Inherent depot- and age-dependent preadipocyte characteristics may contribute to age-related fat redistribution. Both aging and depot origin affect preadipocyte replication and adipogenesis. To define responsible mechanisms, we analyzed genome-wide expression profiles in epididymal (E) and perirenal (P) preadipocytes cultured from young (3 month) and old (30m) rats. Differences between depots were distinct from and more dramatic than those that occur with aging.
Keywords: cell type and age comparison
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| Overall design |
Preadipocytes were isolated from perirenal and epididymal fat depots of 3 young (3 month) and 3 old (30 month) Brown Norway rats for a total of 12 samples from 6 different animals.
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| Contributor(s) |
Lenburg ME, Schlauch KA, Kirkland JL, Cartwright MJ, Pirstskhalava T, Tchkonia T, Cartwright A |
| Citation(s) |
20106964 |
| Submission date |
Jan 10, 2007 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Marc E. Lenburg |
| E-mail(s) |
mlenburg@bu.edu
|
| Phone |
617-414-1375
|
| Fax |
617-414-1646
|
| URL |
http://gg.bu.edu
|
| Organization name |
Boston University School of Medicine
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| Department |
Genetics and Genomics
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| Street address |
715 Albany Street, E613B
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02130 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL341 |
[RAE230A] Affymetrix Rat Expression 230A Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA99009 |
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