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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Oct 06, 2007 |
| Title |
Hepatocellular carcinoma follows loss of liver-gender specificity in mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
We are investigating hepatic transcriptional responses associated with castration and tumorigenic hepatitis induced by Helicobacter hepaticus infection in mature male A/JCr mice
Microarray data demonstrated a global loss of gender-dimorphic gene expression regulation in mice with chronic hepatitis and liver cancer
Keywords: dose
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| Overall design |
Male A/JCr mice were inoculated with H. hepaticus or vehicle at 4 weeks; some underwent castration at 1 year, and all were necropsied at 21 months
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| Contributor(s) |
Rogers AB, Theve EJ, Feng Y, Fry RC, Clapp KM, Cormier KS, Fox JG |
| Citation(s) |
18089782 |
| Submission date |
Jan 03, 2007 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Rebecca Catherine Fry |
| E-mail(s) |
rfry@unc.edu
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| Organization name |
UNC-Chapel Hill
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| Department |
Environmental Sciences and Engineering
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| Street address |
1213 MHRC
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| City |
Chapel Hill |
| ZIP/Postal code |
27599 |
| Country |
USA |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (6)
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| GSM153882 |
Mouse sexually intact, uninfected, biological rep1 |
| GSM153883 |
Mouse sexually intact, uninfected, biological rep2 |
| GSM153884 |
Mouse castrated, uninfected, biological rep1 |
| GSM153885 |
Mouse castrated, uninfected, biological rep2 |
| GSM153886 |
Mouse castrated, H. hepaticus, biological rep1 |
| GSM153887 |
Mouse castrated, H. hepaticus, biological rep2 |
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| Relations |
| BioProject |
PRJNA98863 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE6632_RAW.tar |
21.7 Mb |
(http)(custom) |
TAR (of CEL) |
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