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| Status |
Public on Oct 23, 2013 |
| Title |
Expression data from footpad of AIRmax and AIRmin mice submitted to pristane arthritis induction |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Mice selected for high and low acute inflammation were tested for pristane induced arthritis, showing to be susceptible and resistant, respectively.
We used microarrays to detail the global programme of gene expression underlying arthritis progression during induction and identified distinct classes of differentially expressed genes during this process in the footpad of these mice.
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| Overall design |
AIRmax (high inflammation) and AIRmin (low inflammation) mouse footpads were collected for RNA extraction and hybridization on Affymetrix microarrays. We compared control and experimental footpads from male and female AIRmax and AIRmin mice on days 0 and 160, respectively.
Please note that the AIRmax and AIRmin mice were obtained through bidirectional genetic selection, starting with a genetically heterogeneous founder population (F0) produced by intercrossing eight isogenic strains of mice of independent origins (A/J, DBA/2J, P/J, SWR/J, SJL/J, CBA/J, BALB/cJ and C57BL/6J).
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| Contributor(s) |
De Franco M |
| Citation(s) |
24505471 |
| Submission date |
Oct 21, 2013 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Marcelo De Franco |
| E-mail(s) |
marcelo.franco@butantan.gov.br
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| Phone |
551126279519
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| Organization name |
Instituto Butantan
|
| Department |
Imunogenetica
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| Street address |
Avenida Vital Brasil 1500
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| City |
Sao Paulo |
| State/province |
Sao Paulo |
| ZIP/Postal code |
05503900 |
| Country |
Brazil |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA223334 |
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