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Status |
Public on Sep 15, 2013 |
Title |
Gene expression changes due to influenza virus induced miRNAs |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
The goal of this experiment was to determine gene expression changes during influenza A virus infection as the result of expression influenza virus inducible miRNAs in A549 cells.
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Overall design |
The gene expression profiling experiment was performed with 4 groups (mock infected, influenza A virus infected, influenza A virus infected in the presence of exogenous miR-141, miR-374b, miR-449b, miR-518b, and miR-1263, and influenza A virus infected in the presence of exogenous miR-147b, miR-190b, miR-199a, miR-512-5p, and miR-874 with 3 biological replicates for each group. Total RNA was purified from A549 cells that were mock infected or infected with influenza A virus (A/WSN/33, 5pfu/cell) alone or in the presence of miRNA mimics 10 hours after treatment.
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Contributor(s) |
Buggele WA |
Citation(s) |
24086750 |
Submission date |
Jun 13, 2013 |
Last update date |
Aug 13, 2018 |
Contact name |
William Buggele |
Organization name |
Northwestern University
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Street address |
2200 Campus Dr.
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City |
Evanston |
State/province |
IL |
ZIP/Postal code |
60208 |
Country |
USA |
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Platforms (1) |
GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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Samples (12)
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GSM1160916 |
A/WSN/33 Infected Replicate 1 |
GSM1160917 |
A/WSN/33 Infected Replicate 2 |
GSM1160918 |
A/WSN/33 Infected Replicate 3 |
GSM1160919 |
A/WSN/33 Infected with miRNA Mimics miR-141, miR-374b, miR-449b, miR-518b, and miR-1263 Replicate 1 |
GSM1160920 |
A/WSN/33 Infected with miRNA Mimics miR-141, miR-374b, miR-449b, miR-518b, and miR-1263 Replicate 2 |
GSM1160921 |
A/WSN/33 Infected with miRNA Mimics miR-141, miR-374b, miR-449b, miR-518b, and miR-1263 Replicate 3 |
GSM1160922 |
A/WSN/33 Infected with miRNA Mimics miR-147b, miR-190b, miR-199a, miR-512-5p, and miR-874 Replicate 1 |
GSM1160923 |
A/WSN/33 Infected with miRNA Mimics miR-147b, miR-190b, miR-199a, miR-512-5p, and miR-874 Replicate 2 |
GSM1160924 |
A/WSN/33 Infected with miRNA Mimics miR-147b, miR-190b, miR-199a, miR-512-5p, and miR-874 Replicate 3 |
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Relations |
BioProject |
PRJNA208800 |
Supplementary file |
Size |
Download |
File type/resource |
GSE47937_RAW.tar |
26.2 Mb |
(http)(custom) |
TAR |
Processed data provided as supplementary file |
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