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| Status |
Public on Dec 31, 2013 |
| Title |
IMR90 lung fibroblasts treated with IL-4 or IL-13 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
IL-4 and IL-13 are cytokines involved in type 2 immune responses involved in atopic asthma and other diseases. They have a partially overlapping set of cognate receptors whose roles are incompletely understood. Here we explore the effects of these cytokines on lung fibroblasts in order to assess the global similarities and contrasts in the genes whose expression their ligation modulates.
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| Overall design |
IMR-90 lung fibroblast cells were cultured on matrigel or plastic and treated for 24 hours with IL-4 (10 ng/ml), IL-13 (10ng/ml), or TNFa (10 ng/ml) before harvest.
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| Contributor(s) |
Abbas AR, Arron JR, Chandriani S |
| Citation(s) |
24879793 |
| Submission date |
May 30, 2013 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Alex Abbas |
| E-mail(s) |
abbas@gene.com
|
| Organization name |
Genentech, Inc.
|
| Department |
Bioinformatics
|
| Street address |
1 DNA Way
|
| City |
South San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94080 |
| Country |
USA |
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| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA206009 |
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