|
| Status |
Public on Jan 26, 2013 |
| Title |
Role of Gα(olf) in Familial and Sporadic Adult-Onset Primary Dystonia |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression studies were performed to identify pathways possibly dysregulated by mutant in the gene Gα(olf). These experiments employed RNA derived from lymphoblastoid cell lines established for 4 affected carriers and 4 non-carriers.
In comparison to endogenous control and other dystonia-associated genes, GNAL was expressed at relatively low levels in lymphoblastoid cell lines.
|
| |
|
| Overall design |
Comparison of whole blood expression profiles of mutation carrying dystonia patients with normal controls
|
| |
|
| Contributor(s) |
Vemula SR, LeDoux MS |
| Citation(s) |
23449625 |
| Submission date |
Jan 25, 2013 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Satya Vemula |
| E-mail(s) |
svemula@uthsc.edu
|
| Organization name |
University of Tennessee Health Science Center
|
| Department |
Neurology
|
| Street address |
855 Monroe Avenue, Suite 415 Link Building
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38163 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA187370 |
Less...
More...