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Series GSE42939 Query DataSets for GSE42939
Status Public on Dec 16, 2012
Title An integrative genomic and transcriptomic analysis reveals potential targets associated with cell proliferation in uterine leiomyomas
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Transcriptional profiling of uterine leiomyoma tumor samples for integrative analysis with copy number alterations data. Goal was to identify up- and/or down-expressed genes associated with genomic gains and/or losses, respectively. After, it was applied to GSEA and CONEXIC algorithm to integrate the data. Protein-protein interactions also was building and the data were validated using qRT-PCR and IHC techniques.
 
Overall design Experiment condition, 51 uterine leiomyoma samples from patients at the secretory or proliferative menstrual cycle phases were labeled with Cy3 and adjacent normal myometrium reference samples were labeled with Cy5. Each uterine leiomyoma and adjacent normal myometrium sample were obtained from the same patient and were mixed and hybridized on a glass slide Agilent 4x44 platform.
 
Contributor(s) Cirilo PD, Marchi FA
Citation(s) 23483937
Submission date Dec 14, 2012
Last update date Jan 23, 2019
Contact name Priscila Daniele Ramos Cirilo
Organization name Instituto de Biociências de Botucatu
Department Genética
Lab NeoGene
Street address Distrito de Rubião Junior S/N
City Botucatu
State/province SP
ZIP/Postal code 18618-970
Country Brazil
 
Platforms (1)
GPL6480 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
Samples (51)
GSM1053611 Uterine leoimyoma tumor_729TC_Secretory
GSM1053612 Uterine leoimyoma tumor_684T_Secretory
GSM1053613 Uterine leoimyoma tumor_317T_2_Secretory
Relations
BioProject PRJNA183922

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE42939_RAW.tar 646.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
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