|
| Status |
Public on Apr 24, 2013 |
| Title |
Deriving Dopaminergic Neurons for Clinical Use. A Practical Approach. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Identification of new small molecules that regulate the step-wise differentiation of hPSC into dopaminergic neurons population. Furthermore, the naturally occurring steroid, guggulsterone, was found to be the most effective inducer of neural stem cells into dopaminergic neurons.
|
| |
|
| Overall design |
Total RNA extracted at different stages of neural differentiation from human pluripotent stem cells
|
| |
|
| Contributor(s) |
Gonzalez R, Garitaonandia I, Abramihina T, Wambua GK, Ostrowska A, Brock M, Noskov A, Boscolo FS, Craw JS, Laurent LC, Snyder E, Semechkin R |
| Citation(s) |
23492920 |
| Submission date |
Nov 13, 2012 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Francesca Boscolo |
| E-mail(s) |
francesca.boscolo@gmail.com
|
| Organization name |
UCSD
|
| Department |
Reproductive Medicine
|
| Lab |
Marianna Alperin
|
| Street address |
9500 Gilman Drive
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92122 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (7)
|
| GSM1036447 |
Human Pluripotent Stem cell cultured in feeder free condition (Matrigel) with Stempro Media Replicate 1 |
| GSM1036448 |
Human Pluripotent Stem cell cultured in feeder free condition (Matrigel) with Stempro Media Replicate 2 |
| GSM1036449 |
Neural Stem Cells cultured in feeder free condition (Matrigel) with NSC Media Replicate 1 |
| GSM1036450 |
Neural Stem Cells cultured in feeder free condition (Matrigel) with NSC Media Replicate 2 |
| GSM1036451 |
Mature dopaminergic neurons cultured in neurobasal Media Replicate 1 |
| GSM1036452 |
Mature dopaminergic neurons cultured in neurobasal Media Replicate 2 |
| GSM1036453 |
Brain tissue |
|
| Relations |
| BioProject |
PRJNA179491 |
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