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Status |
Public on Aug 01, 2013 |
Title |
Combinatorial treatment of DNMT inhibitor and LSD1 inhibitor results in cell growth inhibition and reexpression of epigenetically silenced genes (gene expression) |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
|
Summary |
A combinatorial treatment consisting of a DNMTi and a LSD1i shows synergistic effects in reactivating aberrantly silenced genes by enriching H3K4me2 and H3K4me.
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Overall design |
24 Samples consisting of 3 cell lines hybridised to the Illumina HumanHT-12 V4.0 Beadchip.
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Contributor(s) |
Han H, Yang X |
Citation(s) |
24040395 |
Submission date |
Oct 17, 2012 |
Last update date |
Aug 13, 2018 |
Contact name |
Xiaojing Yang |
E-mail(s) |
xiaojiny@usc.edu
|
Phone |
(323)865-0740
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Organization name |
USC/Norris Comprehensive Cancer Center
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Street address |
1441 Eastlake Ave, Room 7336
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City |
Los Angeles |
State/province |
CA |
ZIP/Postal code |
90033 |
Country |
USA |
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Platforms (1) |
GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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Samples (24)
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This SubSeries is part of SuperSeries: |
GSE41754 |
Combinatorial treatment of DNMT inhibitor and LSD1 inhibitor results in cell growth inhibition and reexpression of epigenetically silenced genes |
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Relations |
BioProject |
PRJNA178110 |