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| Status |
Public on Dec 01, 2016 |
| Title |
System Analysis: Respiratory Syncytial Virus induces a decrease expression of HLA-DR at both the cell surface and transcriptional level in Infants with Severe Bronchiolitis. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
The objective of this study was to better understand the immune response to RSV at the port of entry, in the upper respiratory tract mucosa of children naturally infected with RSV.
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| Overall design |
For the present study, we collected Nasal wash samples from a total of 76 naturally infected RSV infants within 48 hours of hospital admission and 10 healthy controls. After sample collected, samples were process and RNA was extracted for further microarray hybridization.
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| Contributor(s) |
Lopez SC, Flano E, Suarez-Arrabal MC, Mertz SE, Mella C, Dimo B, Arthur G, Ramilo O, Mejias A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 05, 2012 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Santiago Lopez |
| E-mail(s) |
santiago.lopez@nationwidechildrens.org
|
| Phone |
614-722-2694
|
| Organization name |
The Research Institute at the Nationwide Children's Hospital
|
| Department |
Center for Vaccines & Immunity
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| Lab |
Ramilo & Mejias
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| Street address |
700 Children's dr.
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| City |
Columbus |
| State/province |
OH |
| ZIP/Postal code |
43205 |
| Country |
USA |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (86)
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| Relations |
| BioProject |
PRJNA177118 |
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