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Series GSE39646 Query DataSets for GSE39646
Status Public on Oct 10, 2012
Title Effects of PD-0332991 on gene expression of human pancreatic ductal adenocarcinoma (PDAC) cell lines
Organism Homo sapiens
Experiment type Expression profiling by array
Summary PD-0332991 is a small molecule inhibitor for Cdk4 and Cdk6. It exerted growth inhibitory effects on PDAC cell lines (AsPC-1 and COLO-357). Microarray analysis was used to characterize the changes in gene expression profiles of AsPC-1 and COLO-357 upon PD-0332991 incubation
 
Overall design AsPC-1 and COLO-357 cells were treated in the absence or presence of 5 µM PD-0332991 for 24 h and 72 h. Each expreimental condition had biological triplicates. Twenty-four samples were analyzed in total.
 
Contributor(s) Liu F, Korc M
Citation(s) 22869556
Submission date Jul 25, 2012
Last update date Aug 13, 2018
Contact name Fang Liu
E-mail(s) fang.liu@dartmouth.edu
Organization name Indiana University
Department Endocrinology
Lab Korc Lab
Street address Walnut street
City Indianapolis
State/province IN
ZIP/Postal code 46202
Country USA
 
Platforms (1)
GPL10558 Illumina HumanHT-12 V4.0 expression beadchip
Samples (24)
GSM973694 AsPC-1_vehicle control 24 h_rep1
GSM973695 AsPC-1_vehicle control 24 h_rep2
GSM973696 AsPC-1_vehicle control 24 h_rep3
Relations
BioProject PRJNA171328

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39646_RAW.tar 26.2 Mb (http)(custom) TAR
GSE39646_full_list_significantly_changed_genes.xls.gz 63.9 Kb (ftp)(http) XLS
GSE39646_non-normalized.txt.gz 3.9 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record
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