|
| Status |
Public on Dec 26, 2005 |
| Title |
CD3+ T cells derived from bone marrow or peripheral blood of aplastic anemia patients |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
CD3+ T cells derived from bone marrow aspirates and peripheral blood samples of newly diagnosed AA patients and healthy volunteers were analysed using Affymetrix HG_U133A GeneChips. Additionally, two patients were studied after achieving a partial remission (post-Therapy).
Keywords: disease vs health vs response to therapy
|
| |
|
| Overall design |
Altogether, we analysed 8 different samples. Pool I contained three female and one male patients, 19 to 70 years old, suffering from (severe) aplastic anemia. From these four donors, samples derived from bone marrow aspirates and from peripheral blood, were pooled on total-RNA basis. Pool II consisted of additional two patients, one male (64 years old) and one female (70 years old). From both donors, total-RNA was extracted and pooled from CD3+ T cells derived either from bone marrow or peripheral blood, each prior and post therapy. Healthy control pools included three donors for the peripheral blood sample and two donors for bone marrow derived T cells.
|
| |
|
| Citation(s) |
17052335 |
| Submission date |
Dec 12, 2005 |
| Last update date |
Aug 29, 2019 |
| Contact name |
Susanne Pfoertner |
| E-mail(s) |
susanne.pfoertner@gbf.de
|
| Organization name |
German Research Centre for Biotechnology (GBF)
|
| Street address |
Mascheroder Weg 1
|
| City |
Braunschweig |
| ZIP/Postal code |
38124 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA94009 |
Less...
More...