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| Status |
Public on Feb 08, 2006 |
| Title |
Human cerebellum, frontal cortex [BA4, BA9] and caudate nucleus HD tissue experiment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Post mortem human brain tissue comparison between HD patients and controls from 3 brain regions - cerebellum, frontal cortex [BA4, BA9] and caudate nucleus. Gene expression analysed using linear models from LIMMA package in Bioconductor suite.
Keywords: disease state analysis
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| Overall design |
Large sample sizes were used to examine brain tissue gene expression at various stages of HD pathology. Three brain regions were profiled, compared and analysed for differential gene expression. The broad aim was to capture early stage gene expression changes in HD brains.
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| Contributor(s) |
Hodges A, Strand AD, Aragaki AK, Kuhn A, Sengstag T, Hughes G, Elliston LA, Hartog C, Goldstein DR, Thu D, Hollingsworth ZR, Collin F, Synek B, Holmans PA, Young AB, Wexler NS, Delorenzi M, Kooperberg C, Augood SJ, Faull RL, Olson JM, Jones L, Luthi-Carter R |
| Citation(s) |
16467349, 16623940 |
| Submission date |
Dec 08, 2005 |
| Last update date |
Aug 29, 2019 |
| Contact name |
Lesley Jones, Angela Hodges |
| E-mail(s) |
jonesl1@cf.ac.uk, Angela.Hodges@iop.kcl.ac.uk
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| Phone |
+44 2920 745175
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| Organization name |
Cardiff University School of Medicine
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| Department |
Psychological Medicine
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| Street address |
Heath Park
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| City |
Cardiff |
| ZIP/Postal code |
CF14 4XN |
| Country |
United Kingdom |
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| Platforms (2) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
| GPL97 |
[HG-U133B] Affymetrix Human Genome U133B Array |
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| Samples (404)
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| Relations |
| BioProject |
PRJNA93987 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE3790_RAW.tar |
1.4 Gb |
(http)(custom) |
TAR (of CEL) |
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