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Series GSE34876 Query DataSets for GSE34876
Status Public on Nov 01, 2012
Title Genome-wide analysis of Human Upf1, SMG5, SMG7 and PNRC2 downregulated substrates in HeLa cell
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Analysis of cellular NMD (Nonsense-mediated mRNA decay) substrates that regulated by Upf1, SMG5, SMG7 and/or PNRC2 in HeLa cell. The hypothesis tested in the present study was that endogenous NMD substrates may co-regulated by Upf1, SMG5, SMG7 and PNRC2.
 
Overall design Total RNA obtained from HeLa cells with downregulation of Upf1, SMG5, PNRC2 or SMG7 by siRNA. The up- or down-regulated transcripts were compare to control siRNA treated HeLa cell RNA extract. Significant transcripts were confirmed by replication
 
Contributor(s) Cho H, Han S, Choe J
Citation(s) 23234702
Submission date Jan 05, 2012
Last update date Aug 13, 2018
Contact name Hana Cho
E-mail(s) sweet-akasia@hanmail.net
Phone 82-2-3290-3919
Organization name Korea University
Department School of Life Sciences and Biotechnology
Lab Molecular Genomics
Street address Anam 5ga, Sungbukku
City Seoul
ZIP/Postal code 136-701
Country South Korea
 
Platforms (1)
GPL10558 Illumina HumanHT-12 V4.0 expression beadchip
Samples (10)
GSM856819 Control siRNA_treated rep 1
GSM856820 Upf1 siRNA_treated rep 1
GSM856821 SMG5 siRNA_treated rep 1
Relations
BioProject PRJNA150109

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE34876_RAW.tar 26.2 Mb (http)(custom) TAR
GSE34876_non-normalized.txt 9.0 Mb (ftp)(http) TXT
Processed data included within Sample table

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