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| Status |
Public on Dec 03, 2013 |
| Title |
Expression data from mouse intestine: BALB/c MTHFR+/+ on control diet vs BALB/c MTHFR+/- on folate deficient diet |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Previous studies in our laboratory have shown that low folate diet (control diet with 2mg folate/kg, low folate diet with 0.3mg folate/kg) can induce intestinal tumors in BALB/c mice.
We used microarrays to compare MTHFR+/+ BALB/c mice fed control diet and MTHFR+/- BALB/c mice fed low folate diet.
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| Overall design |
After weaning, 4 BALB/c Mthfr +/+ mice were fed with a control diet (CD, 2mg folate/kg) and 4 BALB/c Mthfr +/- mice were fed a low folate diet (FD, 0.3mg folate/kg) for 1 year. Both diets contain succinylsulfanthiozole (1%) to prevent folate synthesis by intestine microbial biota.
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| Contributor(s) |
Cao Y, Leclerc D |
| Citation(s) |
24169962 |
| Submission date |
Nov 29, 2011 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Daniel Leclerc |
| E-mail(s) |
daniel.leclerc@mail.mcgill.ca
|
| Phone |
514-412-4400 x23281
|
| Fax |
514-412-4331
|
| Organization name |
Montreal Children's Hospital
|
| Department |
Medical Genetics, Room 242
|
| Lab |
Rima Rozen Laboratory
|
| Street address |
4060 Ste-Catherine West
|
| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H3Z 2Z3 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (8)
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| GSM840458 |
BALB/c intestine CD MTHFR+/+ biological rep1 |
| GSM840459 |
BALB/c intestine CD MTHFR+/+ biological rep2 |
| GSM840460 |
BALB/c intestine CD MTHFR+/+ biological rep3 |
| GSM840461 |
BALB/c intestine CD MTHFR+/+ biological rep4 |
| GSM840462 |
BALB/c intestine FD MTHFR+/- biological rep1 |
| GSM840463 |
BALB/c intestine FD MTHFR+/- biological rep2 |
| GSM840464 |
BALB/c intestine FD MTHFR+/- biological rep3 |
| GSM840465 |
BALB/c intestine FD MTHFR+/- biological rep4 |
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| Relations |
| BioProject |
PRJNA150595 |
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