|
| Status |
Public on Nov 14, 2012 |
| Title |
Gene expression profile changes in brains of VSV-infected wild-type and Ifit2 knockout mice at 6 days after infection |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Vesicular stomatitis virus replicates with marked effciency in Ifit2 knockout mouse brains late after infection (6 days after intranasal inoculation), compared to wt brains. Changes in gene expression, especially of interferon-stimulated genes, between late in infection (at 6 d p.i.) compared to early during infection (2 d p.i.) were examined in comparison to wild-type.
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| |
|
| Overall design |
Total RNA extracted from mouse brains of wt or Ifit2 knockout mice at 6 days after infection, compared to RNA from 2 days after infection.
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| |
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| Contributor(s) |
Sen GC |
| Citation(s) |
22615570 |
| Submission date |
Nov 14, 2011 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Ganes C. Sen |
| E-mail(s) |
seng@ccf.org
|
| Organization name |
Cleveland Clinic
|
| Street address |
9500 Euclid Avenue NE-20
|
| City |
Cleveland |
| ZIP/Postal code |
44195 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
|
| Samples (4)
|
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| Relations |
| BioProject |
PRJNA148299 |
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