|
| Status |
Public on Dec 31, 2011 |
| Title |
Whole-transcript expression data for uveal melanoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
G protein alpha q and 11 are mutated in 90% of uveal melanoma and they activate the MAPK pathway. Using expression microarray analysis, we identified a unique MEK dependent transcriptional signature with genes that are involved in proliferation and tumor cell invasion.
|
| |
|
| Overall design |
Uveal melanoma cells were profiled on Illumina Human HT-12 arrays per manufacturer's instructions
|
| |
|
| Citation(s) |
22550165 |
| Submission date |
Nov 13, 2011 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Brian Denton |
| E-mail(s) |
dentonb@mskcc.org
|
| Organization name |
Memorial Sloan-Kettering Cancer Center
|
| Department |
Epidemiology and Biostatistics
|
| Street address |
307 E. 63rd Street
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10065 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (29)
|
|
| Relations |
| BioProject |
PRJNA148641 |
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