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| Status |
Public on Jul 01, 2006 |
| Title |
Effect of chronic ethanol consumption on rat pancreas |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Male Wistar rats weighing 90-120 g were acclimatized for one week and fed standard laboratory chow, at which time the animals were divided into two groups. Animals were then pair-fed for 8 weeks a regular laboratory chow and water “ad libitum” or Lieber-DeCarli diet (36% calories from ethanol). Control animals received the iso-caloric amount of dextrose to replace ethanol. After 8 weeks of differential feeding rats were euthanized, the pancreas immediately dissected and stored at -80?C until RNA isolation. RNA expression was analyzed using Affymetrix RAE230A gene chips
Keywords: stress response, disease state analysis
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| Overall design |
pancreas from 3 rats feed control diets and 3 rats feed ethanol diets were analyzed
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| Contributor(s) |
Logsdon CD, Kubisch CH, Gukovsky I, Lugea A, Tsukamoto H, Pandol SJ, Kuick R, Misek DE, Hanash SM |
| Citation(s) |
16804415 |
| Submission date |
Sep 15, 2005 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Rork Kuick |
| E-mail(s) |
rork@umich.edu
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| Phone |
734-936-9241
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| Organization name |
University of Michigan
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| Street address |
University of Michigan, SPH II, 1415 Washington Heights, Room M2533
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| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48109-2029 |
| Country |
USA |
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| Platforms (1) |
| GPL341 |
[RAE230A] Affymetrix Rat Expression 230A Array |
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| Samples (6)
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| GSM74493 |
pancreas, control diet, replicate 1 |
| GSM74494 |
pancreas, control diet, replicate 2 |
| GSM74495 |
pancreas, control diet, replicate 3 |
| GSM74496 |
pancreas, ethanol diet, replicate 1 |
| GSM74497 |
pancreas, ethanol diet, replicate 2 |
| GSM74498 |
pancreas, ethanol diet, replicate 3 |
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| Relations |
| BioProject |
PRJNA93341 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE3311_RAW.tar |
14.4 Mb |
(http)(custom) |
TAR (of CEL) |
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