|
| Status |
Public on May 30, 2012 |
| Title |
Bisquinolinium Compounds Induce Quadruplex-Specific Transcriptome Changes in HeLa S3 Cell Line |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The effect of bisquinolinium compounds PhenDC3 and 360A genome wide gene expression changes modulated via promoter based G-quadruplex (G4) motifs.
|
| |
|
| Overall design |
The total RNA was extracted after treating HeLa S3 cells with 10 µM of no molecule (DMSO), 8979A (control molecule), PhenDC3 (G4 specific molecule) or 360A (G4 specific molecule) for 48 hrs in triplicate.
|
| |
|
| Contributor(s) |
Halder R, Hartig JS |
| Citation(s) |
22414013 |
| Submission date |
Sep 15, 2011 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Joerg Hartig |
| E-mail(s) |
joerg.hartig@uni-konstanz.de
|
| Phone |
+49-7531-88-4575
|
| Organization name |
University of Konstanz
|
| Department |
Dept. of Chemistry
|
| Lab |
AG HArtig
|
| Street address |
Universitätsstr. 10
|
| City |
Konstanz |
| ZIP/Postal code |
78457 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (12)
|
| GSM797472 |
HeLa no-molecule 48 hrs Replicate 1 |
| GSM797473 |
HeLa no-molecule 48 hrs Replicate 2 |
| GSM797474 |
HeLa no-molecule 48 hrs Replicate 3 |
|
| Relations |
| BioProject |
PRJNA147423 |
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