|
| Status |
Public on Jun 01, 2012 |
| Title |
Adaptation During Ovarian Cancer Metastasis Reveals a Predictive Gene Signature |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We characterized the genetic copy number and expression differences between matched ovarian primary tumors and omental metastases.
Differentially expressed genes revealed that metastases proliferate more and are less apoptotic.
Differentially expressed genes revealed a predictive expression signature when applied to other gene expression datasets.
|
| |
|
| Overall design |
18 samples from 9 matched pairs of primary ovarian tumors and metastases from the omentum were collected.
|
| |
|
| Contributor(s) |
Brodsky AS |
| Citation(s) |
24732363 |
| Submission date |
Jul 12, 2011 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Alexander Brodsky |
| E-mail(s) |
alex_brodsky@brown.edu
|
| Phone |
401-444-1649
|
| Organization name |
Rhode Island Hospital/Brown University
|
| Department |
MCB
|
| Lab |
Brodsky lab
|
| Street address |
593 Eddy St.
|
| City |
PROVIDENCE |
| State/province |
RI |
| ZIP/Postal code |
02903 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (18)
|
|
| Relations |
| BioProject |
PRJNA144573 |
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