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| Status |
Public on May 02, 2012 |
| Title |
Expression data from Top2β KO cells as well ICRF-193 treatment of in vitro derived neurons and cortical glutamatergic neurons |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Expression profiling of from Top2β knokout and ICRF-193 treated neurons reveals a significant number of genes that are transcriptionally deregulated
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| |
|
| Overall design |
Gene expression in the Top2β knocnout ES, NP and TN stages of stem cell differention to the corresponidng wild type cells. In vitro derived neurons and cortical glutamatergic neurons were either treated with DMSO or ICRF-193 and were compared to reveal differentially expressed genes.
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| |
|
| Contributor(s) |
Tiwari V, Burger L |
| Citation(s) |
22474351 |
| Submission date |
Feb 11, 2011 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Dirk Schuebeler |
| Organization name |
Friedrich Miescher Institute for Biomedical Research
|
| Street address |
Maulbeerstrasse 66
|
| City |
Basel |
| ZIP/Postal code |
4058 |
| Country |
Switzerland |
| |
|
| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (28)
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| This SubSeries is part of SuperSeries: |
| GSE27247 |
Topoisomerase IIbeta occupies H3K4 methylated sites and regulates neuronal survival via repression of the neurotrophin receptor p75 |
|
| Relations |
| BioProject |
PRJNA141813 |
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