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| Status |
Public on May 16, 2024 |
| Title |
Transcriptome analysis of JMML patients compare to healthy prenatal and postnatal samples. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
JMML (Juvenile myelomonocytic leukaemia) is a leukaemia that only develops in young children and is thought to have a prenatal initiation. To study the relationship between JMML and normal ontogeny we studied the transcriptome of HPC (hematopoietic progenitor cells) sorted from sporadic JMML patients, healthy prenatal samples and from healthy age matched donors. Bulk transcriptome of sorted HPC reveals that some JMML samples cluster with prenatal samples whereas other from a distinct cluster apart from any healthy samples.
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| |
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| Overall design |
Bulk RNAseq data on sorted HPC.
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| |
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| Contributor(s) |
Cavé H, Strullu M, Caye A, Arfeuille C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
May 16, 2024 |
| Last update date |
May 18, 2024 |
| Contact name |
Chloé Arfeuille |
| E-mail(s) |
chloe.arfeuille@aphp.fr
|
| Phone |
0632389521
|
| Organization name |
APHP
|
| Street address |
48, boulevard Sérurier
|
| City |
Paris |
| ZIP/Postal code |
75019 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (75)
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| Relations |
| BioProject |
PRJNA1112163 |
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