|
| Status |
Public on Nov 12, 2011 |
| Title |
Vaginal epithelial gene expression in postmenopausal women suffering from vaginal dryness |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The onset of menopause is accompanied by a dramatic increase in reported symptoms of vaginal dryness, soreness, irritation or itching, pain with intercourse and bleeding after intercourse. Collectively these affect 25-50% of women of post-menopausal age and significantly impact their quality of life. To examine how gene expression differs between these groups, surface vaginal epithelial cells were collected from postmenopausal women suffering from vaginal dryness and appropriate controls not suffering from dryness.
Affymetrix GeneChip Human 1.0 ST microarrays were performed on RNA isolated from ten participants.
|
| |
|
| Overall design |
Suitable RNA was extracted from ten participants which were classified into two groups, the dryness and control groups, based on diagnosis of dryness by a nurse during gynecoligical examination.
|
| |
|
| Contributor(s) |
Reid G, Bisanz JE |
| Citation(s) |
22073175 |
| Submission date |
Jan 20, 2011 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Jordan Eduard Bisanz |
| E-mail(s) |
jbisanz@uwo.ca
|
| Organization name |
Lawson Health Research Institute
|
| Street address |
268 Grosvenor Street, Room F2-116
|
| City |
London |
| State/province |
Ontario |
| ZIP/Postal code |
N6A 4V2 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA136309 |
Less...
More...