|
| Status |
Public on May 01, 2024 |
| Title |
EGR2 biases the differentiation of liver infiltrating monocytes into hLAMs. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This analysis was performed to understand the heterogeneity and differentiation pathway of monocyte-derived macrophages.
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| |
|
| Overall design |
A single cell RNA-seq analysis of CD45.2+Lin (CD90.2, B220, NK1.1, SiglecF)-CD11b+ liver innate immune cells from one ND-fed WT mouse, one ND-fed EGR2-KO mouse, one CDA-HFD-fed WT mouse, and one CDA-HFD-fed EGR2-KO mouse.
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| |
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| Contributor(s) |
Iwata A, Shichino S, Seki T, Asano K |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 15, 2024 |
| Last update date |
May 02, 2024 |
| Contact name |
Kenichi Asano |
| E-mail(s) |
asanok@toyaku.ac.jp
|
| Organization name |
Tokyo University of Pharmacy and Life Sciences
|
| Department |
Life Sciences
|
| Lab |
Immune Regulation
|
| Street address |
1432-1 Horinouchi
|
| City |
Hachioji |
| State/province |
Tokyo |
| ZIP/Postal code |
1920392 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (2) |
| GSM8208193 |
Liver innate immune cells, mRNA-derived cDNA, lane 1 |
| GSM8208194 |
Liver innate immune cells, HTO-derived cDNA, lane 1 |
|
| Relations |
| BioProject |
PRJNA1100490 |
