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| Status |
Public on May 16, 2024 |
| Title |
Region-specific pathogenesis and dissipation of intraregional heterogeneity in cerebellar neurodegeneration |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Heterogeneity and selective vulnerability are among the key features of the healthy and diseased brain. Cerebellum contains majority of brain cells, and is thought to be relatively uniform in structure. We explore heterogeneity in the context of healthy cerebellum and during selective vulnerability in cerebellar disease.
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| |
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| Overall design |
RNA-seq of cerebellar tissues in WT and SCA1 mice.
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| |
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| Contributor(s) |
Hamel K, Labrada Moncada E, Sheeler C, Rosa JG, Gilliat S, Zhang Y, Cvetanovic M |
| Citation(s) |
38750673 |
| Submission date |
Feb 12, 2024 |
| Last update date |
May 16, 2024 |
| Contact name |
Ying Zhang |
| E-mail(s) |
yingzhang@umn.edu
|
| Phone |
6126243737
|
| Organization name |
University of Minnesota
|
| Department |
Minnesota Supercomputing Institute
|
| Street address |
117 Pleasant St S.E.
|
| City |
Minneapolis |
| State/province |
MN |
| ZIP/Postal code |
55455 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (49)
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| Relations |
| BioProject |
PRJNA1075799 |
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