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| Status |
Public on Oct 27, 2010 |
| Title |
Expression profile of early stage in OKS mediated reprogramming regulated by Sox2 and Klf4 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Klf4 and Sox2 are among the core reprogramming factor, and have different function in reprogramming. Klf4 is supposed to trigger MET in the early stage of reprogramming ,Sox2 is well known plutipotent relative gene.
Klf4 and Sox2 play important role in induced reprogramming. We performed this experiment to identify the targets regulated by Sox2 and Klf4 respectively.
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| Overall design |
We perform a expression profile analysis at Day3 between OK plus TetOn-Sox2 infected MEFs and OS plus TetOn-Klf4 infected MEFs in iCD1(a optimized medium for robust reprograming) medium with or without Dox.
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| Contributor(s) |
Chen J, Pei D, Liu J |
| Citation(s) |
21135873 |
| Submission date |
Oct 26, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
liu jing |
| E-mail(s) |
liu_jing@gibh.ac.cn
|
| Organization name |
GIBH
|
| Street address |
190 Kai Yuan Avenue
|
| City |
Guangzhou |
| State/province |
guangdong |
| ZIP/Postal code |
510530 |
| Country |
China |
| |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE24930 |
MEFs, iPS, and ES expression profiles, and OKS mediated reprogramming regulated by Sox2 and Klf4 |
|
| Relations |
| BioProject |
PRJNA133465 |
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