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Series GSE246056 Query DataSets for GSE246056
Status Public on May 09, 2024
Title Gene expression profiles of white bass (Morone chrysops) and hybrid striped bass (M. chrysops x M. saxatilis) gill tissue over time following Flavobacterium covae exposure
Organisms Morone chrysops x Morone saxatilis; Morone chrysops
Experiment type Expression profiling by high throughput sequencing
Summary Columnaris disease is a prevalent disease in freshwater environments worldwide caused by the ubiquitous aquatic bacterium Flavobacterium species. Adhesion to the external mucosal surfaces of fishes is the initial stage of infection, and the gills specifically have been identified as both a primary target and release site for this pathogen. Previous research has indicated that a predominant US aquaculture product, the hybrid striped bass (Morone chrysops x M. saxatilis), is more susceptible to infection with Flavobacterium columnare (covae) than the maternal white bass (M. chrysops) parental species. Therefore, to further elucidate the differences between these fish we conducted a transcriptomic profiling study examining the differences of gene expression in gill mucosal tissue over time after exposure to F. covae isolate LSU-066-04. Combined with previous work, these data provide a greater understanding of host immune response to a common pathogen in moronids.
 
Overall design Gill tissues were sampled from 48 indiviudals at four timepoints prior to (t= 0 hr control) or following exposure to Flavobacterium covae (t= 1 hr, 4 hr, and 24 hr post treatment) (n=24 white bass, WB, and 24 hybrid striped bass, HB, total: 6 of each sampled at each of the four timepoints)
 
Contributor(s) Andersen LK, Abernathy JW
Citation https://doi.org/10.1016/j.cirep.2024.200144
Submission date Oct 23, 2023
Last update date May 09, 2024
Contact name Jason Abernathy
Organization name USDA-ARS
Lab Aquatic Animal Health Research Unit
Street address 990 Wire Road
City Auburn
State/province AL
ZIP/Postal code 36832
Country USA
 
Platforms (2)
GPL30659 HiSeq X Ten (Morone chrysops)
GPL33859 HiSeq X Ten (Morone chrysops x Morone saxatilis)
Samples (48)
GSM7854597 F. columnare challenge hour0 white bass rep1 gill tissue
GSM7854598 F. columnare challenge hour1 white bass rep1 gill tissue
GSM7854599 F. columnare challenge hour4 white bass rep1 gill tissue
Relations
BioProject PRJNA1031191

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Supplementary file Size Download File type/resource
GSE246056_read-counts_wb-hb-flavo.txt.gz 1.4 Mb (ftp)(http) TXT
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Raw data are available in SRA
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