|
| Status |
Public on Jan 02, 2024 |
| Title |
Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple negative breast cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Apigenin reprogrammes the transcriptome of TNBC through alternative splicing thereby exerting anti-proliferative and pro-apoptotic activities. Our findings underscore the potential impact of nutraceuticals for improved TNBC prevention and treatment.
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| |
|
| Overall design |
Comparative alternative splciing analyses of RNA-seq data for triple negative breast cancer MDA-MB-231 cells treated with vehicle or apigenin (DMSO, Api). Twp biological replicates analyzed for both conditions.
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| |
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| Contributor(s) |
Doseff AI, Arango D |
| Citation(s) |
38092740 |
| Submission date |
Sep 05, 2023 |
| Last update date |
Jan 02, 2024 |
| Contact name |
Andrea Doseff |
| E-mail(s) |
doseffan@msu.edu
|
| Organization name |
Michigan State University
|
| Department |
BPS
|
| Lab |
Andrea Doseff
|
| Street address |
4153 BPS, 567 Wilson Rd
|
| City |
East Lansing |
| State/province |
Michigan |
| ZIP/Postal code |
48824 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (6)
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|
| Relations |
| BioProject |
PRJNA1013051 |
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