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| Status |
Public on May 18, 2011 |
| Title |
Nickel Chloride (NiCl2) effect on human T cells from whole blood |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of anti-CD3/anti-CD28 stimulated T cells treated with or without nickel chloride. Nickel is the most important contact allergen in the general population of the industrialized world. Results provide insight into the biological effects of nickel on human CD3+ T cells.
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| Overall design |
We obtained mRNA of purified human CD3+ T cells from 3 different donors that were treated with or without 1000 μM nickel chloride for 1 h and then stimulated with anti-CD3/anti-CD28 for 6 h.
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| Contributor(s) |
Saito R, Hirakawa S, Ohara H, Yasuda M, Yamazaki T, Nishii S, Aiba S |
| Citation(s) |
21569788 |
| Submission date |
Aug 03, 2010 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Rumiko SAITO |
| E-mail(s) |
rumiko-s@med.tohoku.ac.jp
|
| Organization name |
Tohoku University Graduate School of Medicine
|
| Department |
Department of Dermatology
|
| Street address |
1-1 Seiryo-machi, Aoba-ku
|
| City |
Sendai |
| ZIP/Postal code |
980-8574 |
| Country |
Japan |
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| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA131257 |
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