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| Status |
Public on May 01, 2024 |
| Title |
Expression data from ovarian cancer with CHSY1 knockdown |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
CHSY1 has high expression in malignant tumor cells, such as colorectal cancer and ovarian cancer, and is associated with poor prognosis.The proliferation and invasion of ovarian cancer cells are weakened after knocking down CHSY1 with shRNA transfected
We used microarrays to detail the global programme of gene expression underlying CHSY1 knockdown and identified distinct classes of up-regulated and down-regulated genes.
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| Overall design |
Ovarian cancer cells were transfected with shRNA to knockdown CHSY1 for RNA extraction and hybridization on Affymetrix microarrays. Then we got ovarian cancer cells with different CHSY1 expression:shCHSY1(CHSY1 knockdown group) and shCtrl(control group )
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| Contributor(s) |
Huang J, Xia L |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
May 17, 2023 |
| Last update date |
May 01, 2024 |
| Contact name |
Jinling Huang |
| E-mail(s) |
huangjinling@whu.edu.cn
|
| Phone |
+8615623104964
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| Organization name |
Renmin Hospital of Wuhan University
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| Department |
Obstetrics & Gynecology,
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| Street address |
Jiefang Road 238
|
| City |
Wuhan |
| State/province |
Hubei |
| ZIP/Postal code |
430060 |
| Country |
China |
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| Platforms (1) |
| GPL16043 |
GeneChip® PrimeView™ Human Gene Expression Array (with External spike-in RNAs) |
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| Samples (6)
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| GSM7372269 |
ovarian cancer cells knockdown with CHSY1 shRNA-1 |
| GSM7372270 |
ovarian cancer cells knockdown with CHSY1 shRNA-2 |
| GSM7372271 |
ovarian cancer cells knockdown with CHSY1 shRNA-3 |
| GSM7372272 |
ovarian cancer cells knockdown with Control shRNA-1 |
| GSM7372273 |
ovarian cancer cells knockdown with Control shRNA-2 |
| GSM7372274 |
ovarian cancer cells knockdown with Control shRNA-3 |
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| Relations |
| BioProject |
PRJNA973648 |
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