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| Status |
Public on Sep 12, 2023 |
| Title |
Transcriptomic Profile of the Bovine Endosalpinx & Endometrium to Identity Putative Embryokines |
| Organism |
Bos taurus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Although the oviduct and uterus regulate early embryonic development, understanding of the specific maternally-derived molecules that signal to the embryo is incomplete. Objectives of this study were to characterize expression of genes encoding for growth factors, cytokines, and other cell-signaling ligands in the endosalpinx and endometrium of the bovine female and analyze spatial changes in gene expression throughout the reproductive tract.
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| Overall design |
Five adult nulliparous Holstein heifers were synchronized using a 5-day CIDR-Synch protocol. On day 2 after ovulation, animals were slaughtered and samples were collected from the ampulla, upper uterine horn, mid uterine horn, and uterine body of both the contralateral and ipsilateral horns relative to ovulation.
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| Web link |
https://journals.physiology.org/doi/full/10.1152/physiolgenomics.00064.2023
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| Contributor(s) |
Hoorn QA, Rabaglino MB, Maia TS, Sagheer M, Fuego D, Hansen PJ |
| Citation(s) |
37720990 |
| Submission date |
Apr 20, 2023 |
| Last update date |
Dec 01, 2023 |
| Contact name |
Peter Hansen |
| Organization name |
University of Florida
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| Department |
Department of Animal Sciences
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| Street address |
2250 Shealy Drive
|
| City |
Gainesville |
| State/province |
Florida |
| ZIP/Postal code |
32611 |
| Country |
USA |
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| Platforms (1) |
| GPL26012 |
Illumina NovaSeq 6000 (Bos taurus) |
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| Samples (34)
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| Relations |
| BioProject |
PRJNA957752 |
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