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| Status |
Public on Nov 23, 2022 |
| Title |
Developmental effects of neonatal exposure to NOAEL-dose of neonicotinoid clothianidin on the gene expression profiles of hippocampus in male mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The mechanisms of developmental neurotoxicity of neonicotinoid pesticides were not fully understood.
We examined the effects of neonatal exposure to a neonicotinoid pesticide, clothianidin (CLO) on gene expression profiles of the hippocampus in male mice at 3 or 10 weeks of age.
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| Overall design |
Dams were orally administrated no-observed adverse effect level (NOAEL; 65 mg/kg/day) of CLO or vehicle during postnatal day 1 to 4.
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| Contributor(s) |
Hirano T, Shoda A, Hoshi N, Tabuchi Y |
| Citation(s) |
36858607 |
| Submission date |
Nov 22, 2022 |
| Last update date |
May 12, 2023 |
| Contact name |
Tetsushi Hirano |
| E-mail(s) |
thirano@cts.u-toyama.ac.jp
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| Organization name |
University of Toyama
|
| Department |
Life Science Research Center
|
| Street address |
2630 sugitani
|
| City |
Toyama |
| State/province |
Toyama |
| ZIP/Postal code |
939 0194 |
| Country |
Japan |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA904224 |
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