|
| Status |
Public on Nov 01, 2011 |
| Title |
Cultured fibroblasts treated with media from cardiomyocytes. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Investigation of the role of hyaluronan in cardiomyocytes. The aims of the study were to determine if cardiomyocytes are capable of signal to fibroblasts to affect their hyaluronan synthesis and if intracellular signaling causes changes in gene expression.
The study showed that cardiomyocytes send a signal to fibroblasts, to causing them to increase hyaluronan synthesis, with following change in gene expression.
|
| |
|
| Overall design |
Media from cultured cardiomyocytes were transfered to cultured fibroblasts. Gene expression in fibroblasts were analyzed with Illumina Beadstation.
|
| |
|
| Contributor(s) |
Hellman U, Malm L, Ma L, Mörner S, Fu M, Laurent AE, Waldenström A |
| Citation(s) |
21200430 |
| Submission date |
May 05, 2010 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Urban Hellman |
| E-mail(s) |
urban.hellman@medbio.umu.se
|
| Phone |
+46907851621
|
| Organization name |
Umea University
|
| Department |
Public health and clinical medicine
|
| Street address |
Nus 6M
|
| City |
Umea |
| ZIP/Postal code |
90185 |
| Country |
Sweden |
| |
|
| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
|
| Samples (8)
|
| GSM540779 |
Fibroblasts NIH-3T3_unused cardiomyocyte media_rep1 |
| GSM540780 |
Fibroblasts NIH-3T3_unused cardiomyocyte media_rep2 |
| GSM540781 |
Fibroblasts NIH-3T3_unused cardiomyocyte media_rep3 |
| GSM540782 |
Fibroblasts NIH-3T3_media from cardiomyocytes_rep1 |
| GSM540783 |
Fibroblasts NIH-3T3_media from cardiomyocytes_rep2 |
| GSM540784 |
Fibroblasts NIH-3T3_media from cardiomyocytes_rep3 |
| GSM540785 |
Fibroblasts NIH-3T3_ultracentrifuged media from cardiomyocytes_rep1 |
| GSM540786 |
Fibroblasts NIH-3T3_ultracentrifuged media from cardiomyocytes_rep2 |
|
| Relations |
| BioProject |
PRJNA125829 |
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