|
| Status |
Public on Nov 01, 2011 |
| Title |
gonads gene expression profiling in WT and Sox9flox/flox; Sf1:creTr/+ mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
In mammals, gonadal differentiation is the first step of sex determination, and the transcription factor Sox9 promotes testis differentiation. Here we used the XY Sox9flox/flox; Sf1:creTr/+ mouse model and show that the lack of Sox9 expression induces a full sex reversal of E13.5 XY Sox9flox/flox; Sf1:creTr/+ gonads compared to XY Sox9flox/flox.
Keywords: gonads gene expression profiling in WT and Sox9flox/flox; Sf1:creTr/+ mice
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| |
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| Overall design |
3 WT versus 3 Sox9flox/flox; Sf1:creTr/+ mice.
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| |
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| Contributor(s) |
Lavery R, Moreilhon C, Lebrigand K, Barbry P |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
May 04, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Kevin Lebrigand |
| Organization name |
IPMC/CNRS
|
| Lab |
Functional Genomics Platform of Nice-Sophia-Antipolis, France.
|
| Street address |
660 route des lucioles
|
| City |
Valbonne - Sophia-Antipolis |
| ZIP/Postal code |
06560 |
| Country |
France |
| |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (6)
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| Relations |
| BioProject |
PRJNA125925 |
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