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| Status |
Public on Aug 21, 2023 |
| Title |
Systematic mapping of 3D enhancer interactions reveals lineage specific regulatory networks during early mouse developmental decisions [ATAC-Seq] |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
To model and characterize the chromatin regulatory landscape of the very first developmental cell fates, we made use of three previously derived and well-characterized Trophoblast Stem Cell (TSCs), Embryonic Stem Cell (ESC) and Extra Embryonic Stem Cell lines (XENs)
We performed ATAC to map accessible regions (AR) in enhancer and promoter regions in ESC, TSC, XEN and EPISC
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| |
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| Overall design |
Characterization of AR with ATAC-seq for all cell types.
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| |
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| Contributor(s) |
Apostolou E, Polyzos PA |
| Citation(s) |
37577543 |
| Submission date |
Sep 09, 2022 |
| Last update date |
Oct 10, 2023 |
| Contact name |
Effie Apostolou |
| E-mail(s) |
efa2001@med.cornell.edu
|
| Organization name |
Weill Cornell Medicine
|
| Street address |
1161 York Avenue, Apt 8A
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10065 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE213645 |
Systematic mapping of 3D enhancer interactions reveals lineage specific regulatory networks during early mouse developmental decisions |
|
| Relations |
| BioProject |
PRJNA878695 |
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