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| Status |
Public on Apr 19, 2024 |
| Title |
The SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Aug 16, 2022 |
| Last update date |
Apr 19, 2024 |
| Contact name |
Gabriela Alexe |
| E-mail(s) |
galexe@broadinstitute.org
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| Organization name |
Broad Institute
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| Department |
Computational Biology and Bioinformatics
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| Street address |
415 Main St.
|
| City |
Cambridge |
| State/province |
MA |
| ZIP/Postal code |
02142 |
| Country |
USA |
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| Platforms (2) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (92)
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| GSM6467273 |
KELLY cells, DMSO, 6 hours, replicate 1 |
| GSM6467274 |
KELLY cells, DMSO, 6 hours, replicate 2 |
| GSM6467275 |
KELLY cells, DMSO, 6 hours, replicate 3 |
| GSM6467276 |
KELLY cells, dTAG v1 TADA2B, 6 hours, replicate 1 |
| GSM6467277 |
KELLY cells, dTAG v1 TADA2B, 6 hours, replicate 2 |
| GSM6467278 |
KELLY cells, dTAG v1 TADA2B, 6 hours, replicate 3 |
| GSM6467279 |
KELLY cells, DMSO, 24 hours, replicate 1 |
| GSM6467280 |
KELLY cells, DMSO, 24 hours, replicate 2 |
| GSM6467281 |
KELLY cells, DMSO, 24 hours, replicate 3 |
| GSM6467282 |
KELLY cells, dTAG v1 TADA2B, 24 hours, replicate 1 |
| GSM6467283 |
KELLY cells, dTAG v1 TADA2B, 24 hours, replicate 2 |
| GSM6467284 |
KELLY cells, dTAG v1 TADA2B, 24 hours, replicate 3 |
| GSM6467285 |
KELLY cells, DMSO, 72 hours, replicate 1 |
| GSM6467286 |
KELLY cells, DMSO, 72 hours, replicate 2 |
| GSM6467287 |
KELLY cells, DMSO, 72 hours, replicate 3 |
| GSM6467288 |
KELLY cells, dTAG v1 TADA2B, 72 hours, replicate 1 |
| GSM6467289 |
KELLY cells, dTAG v1 TADA2B, 72 hours, replicate 2 |
| GSM6467290 |
KELLY cells, dTAG v1 TADA2B, 72 hours, replicate 3 |
| GSM6467291 |
KELLY cells, CRISPR LACZ, 7 days, replicate 1 |
| GSM6467292 |
KELLY cells, CRISPR LACZ, 7 days, replicate 2 |
| GSM6467293 |
KELLY cells, CRISPR LACZ, 7 days, replicate 3 |
| GSM6467294 |
KELLY cells, CRISPR sg2 TADA2B, 7 days, replicate 1 |
| GSM6467295 |
KELLY cells, CRISPR sg2 TADA2B, 7 days, replicate 2 |
| GSM6467296 |
KELLY cells, CRISPR sg2 TADA2B, 7 days, replicate 3 |
| GSM6467297 |
KELLY cells, CRISPR sg4 TADA2B, 7 days, replicate 1 |
| GSM6467298 |
KELLY cells, CRISPR sg4 TADA2B, 7 days, replicate 2 |
| GSM6467299 |
KELLY cells, CRISPR sg4 TADA2B, 7 days, replicate 3 |
| GSM6467300 |
KELLY cells, CRISPR LACZ, 12 days, replicate 1 |
| GSM6467301 |
KELLY cells, CRISPR LACZ, 12 days, replicate 2 |
| GSM6467302 |
KELLY cells, CRISPR LACZ, 12 days, replicate 3 |
| GSM6467303 |
KELLY cells, CRISPR sg4 TADA2B, 12 days, replicate 1 |
| GSM6467304 |
KELLY cells, CRISPR sg4 TADA2B, 12 days, replicate 2 |
| GSM6467305 |
KELLY cells, CRISPR sg4 TADA2B, 12 days, replicate 3 |
| GSM6467306 |
KELLY cells, CRISPR sg5 TADA2B, 12 days, replicate 1 |
| GSM6467307 |
KELLY cells, CRISPR sg5 TADA2B, 12 days, replicate 2 |
| GSM6467308 |
KELLY cells, CRISPR sg5 TADA2B, 12 days, replicate 3 |
| GSM6506050 |
KELLY-TADA2Bdeg cells, DMSO, HA antibody, 6 hours |
| GSM6506051 |
KELLY-TADA2Bdeg cells, DMSO, Input, 6 hours |
| GSM6506052 |
KELLY-TADA2Bdeg cells, dTAGv1, HA antibody, 6 hours |
| GSM6506053 |
KELLY-TADA2Bdeg cells, dTAGv1, Input, 6 hours |
| GSM6506054 |
NB1-TADA2Bdeg cells, DMSO, HA antibody, 6 hours |
| GSM6506055 |
NB1-TADA2Bdeg cells, DMSO, Input, 6 hours |
| GSM6506056 |
NB1-TADA2Bdeg cells, dTAGv1, HA antibody, 6 hours |
| GSM6506057 |
NB1-TADA2Bdeg cells, dTAGv1, Input, 6 hours |
| GSM6506058 |
NGP-TADA2Bdeg cells, DMSO, HA antibody, 6 hours |
| GSM6506059 |
NGP-TADA2Bdeg cells, DMSO, Input, 6 hours |
| GSM6506060 |
NGP-TADA2Bdeg cells, dTAGv1, HA antibody, 6 hours |
| GSM6506061 |
NGP-TADA2Bdeg cells, dTAGv1, Input, 6 hours |
| GSM6506062 |
KELLY cells, DMSO, H3K9ac antibody, 6 hours |
| GSM6506063 |
KELLY cells, dTAGv1 TADA2B, H3K9ac antibody, 6 hours |
| GSM6506066 |
KELLY cells, DMSO, H3K27ac antibody, 6 hours |
| GSM6506067 |
KELLY cells, dTAGv1 TADA2B, H3K27ac antibody, 6 hours |
| GSM6506070 |
KELLY cells, DMSO, MYCN antibody, 6 hours |
| GSM6506071 |
KELLY cells, dTAGv1 TADA2B, MYCN antibody, 6 hours |
| GSM6506074 |
KELLY cells, DMSO, Input, 6 hours |
| GSM6506075 |
KELLY cells, dTAGv1 TADA2B, Input, 6 hours |
| GSM6506078 |
KELLY cells, DMSO, 48 hours, replicate 1 |
| GSM6506079 |
KELLY cells, DMSO, 48 hours, replicate 2 |
| GSM6506080 |
KELLY cells, DMSO, 48 hours, replicate 3 |
| GSM7871829 |
PROTAC-RNA, KELLY cells, DMSO, 6 hours, replicate 1 |
| GSM7871830 |
PROTAC-RNA, KELLY cells, DMSO, 6 hours, replicate 2 |
| GSM7871831 |
PROTAC-RNA, KELLY cells, DMSO, 6 hours, replicate 3 |
| GSM7871832 |
PROTAC-RNA. KELLY cells, GSK-699-1, 6 hours, replicate 1 |
| GSM7871833 |
PROTAC-RNA. KELLY cells, GSK-699-1, 6 hours, replicate 2 |
| GSM7871834 |
PROTAC-RNA. KELLY cells, GSK-699-1, 6 hours, replicate 3 |
| GSM7871835 |
PROTAC-RNA, KELLY cells, DMSO, 24 hours, replicate 1 |
| GSM7871836 |
PROTAC-RNA, KELLY cells, DMSO, 24 hours, replicate 2 |
| GSM7871837 |
PROTAC-RNA, KELLY cells, DMSO, 24 hours, replicate 3 |
| GSM7871838 |
PROTAC-RNA, KELLY cells, GSK-699-1, 24 hours, replicate 1 |
| GSM7871839 |
PROTAC-RNA, KELLY cells, GSK-699-1, 24 hours, replicate 2 |
| GSM7871840 |
PROTAC-RNA, KELLY cells, GSK-699-1, 24 hours, replicate 3 |
| GSM7871841 |
PROTAC-RNA, KELLY cells, DMSO, 72 hours, replicate 1 |
| GSM7871842 |
PROTAC-RNA, KELLY cells, DMSO, 72 hours, replicate 2 |
| GSM7871843 |
PROTAC-RNA, KELLY cells, DMSO, 72 hours, replicate 3 |
| GSM7871844 |
PROTAC-RNA, KELLY cells, GSK-699-1, 72 hours, replicate 1 |
| GSM7871845 |
PROTAC-RNA, KELLY cells, GSK-699-1, 72 hours, replicate 2 |
| GSM7871846 |
PROTAC-RNA, KELLY cells, GSK-699-1, 72 hours, replicate 3 |
| GSM7871847 |
PROTAC experiment, KELLY cells, DMSO, H3K27ac antibody, 6 hours, replicate 1 |
| GSM7871848 |
PROTAC experiment, KELLY cells, DMSO, H3K27ac antibody, 6 hours, replicate 2 |
| GSM7871849 |
PROTAC experiment, KELLY cells, DMSO, H3K9ac antibody, 6 hours, replicate 1 |
| GSM7871850 |
PROTAC experiment, KELLY cells, DMSO, H3K9ac antibody, 6 hours, replicate 2 |
| GSM7871851 |
PROTAC experiment, KELLY cells, DMSO, Input, 6 hours, replicate 1 |
| GSM7871852 |
PROTAC experiment, KELLY cells, DMSO, Input, 6 hours, replicate 2 |
| GSM7871853 |
PROTAC experiment, KELLY cells, DMSO, MYCN antibody, 6 hours, replicate 1 |
| GSM7871854 |
PROTAC experiment, KELLY cells, GSK6991, H3K27ac antibody, 6 hours, replicate 1 |
| GSM7871855 |
PROTAC experiment, KELLY cells, GSK6991, H3K27ac antibody, 6 hours, replicate 2 |
| GSM7871856 |
PROTAC experiment, KELLY cells, GSK6991, H3K9ac antibody, 6 hours, replicate 1 |
| GSM7871857 |
PROTAC experiment, KELLY cells, GSK6991, H3K9ac antibody, 6 hours, replicate 2 |
| GSM7871858 |
PROTAC experiment, KELLY cells, GSK6991, Input, 6 hours, replicate 1 |
| GSM7871859 |
PROTAC experiment, KELLY cells, GSK6991, Input, 6 hours, replicate 2 |
| GSM7871860 |
PROTAC experiment, KELLY cells, GSK6991, MYCN antibody, 6 hours, replicate 1 |
| GSM7871861 |
PROTAC experiment, KELLY cells, GSK6991, MYCN antibody, 6 hours, replicate 2 |
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| This SuperSeries is composed of the following SubSeries: |
| GSE211354 |
The SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma [RNA-Seq] |
| GSE211953 |
The SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma [ChIP-Seq] |
| GSE211954 |
The SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma [ATAC-Seq] |
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| Relations |
| BioProject |
PRJNA869945 |
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