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| Status |
Public on May 31, 2010 |
| Title |
Ets-1 over-expression in ovarian cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The transcription factor Ets-1 is over-expressed in a wide variety of cancers, and has been strongly associated with the upregulation of factors involved in metastasis and angiogenesis. In this study, we created an inducible Ets-1 over-expressing ovarian cancer cell line from parental 2008 ovarian cancer cells that do not express detectable levels of Ets-1 protein. This microarray compares the stable over-expressing Ets-1 ovarian cancer cell line (2008-Ets1) to their parental 2008 cells to examine differences in gene expression beyond metastasis and angiogenesis.
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| Overall design |
Two samples were used: 2008 ovarian cancer cells, and 2008-Ets1 ovarian cancer cells which over-express Ets-1. Included in this analysis are three independent replicates for each sample.
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| Contributor(s) |
Verschoor ML, Verschoor CP, Singh G |
| Citation(s) |
21042593 |
| Submission date |
Mar 30, 2010 |
| Last update date |
Sep 25, 2019 |
| Contact name |
Meghan Verschoor |
| Organization name |
McMaster University
|
| Department |
Medical Sciences
|
| Lab |
Gurmit Singh Lab
|
| Street address |
699 Concession St
|
| City |
Hamilton |
| State/province |
Ontario |
| ZIP/Postal code |
L8V 5C2 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA126639 |
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