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| Status |
Public on Sep 07, 2023 |
| Title |
Nos1ap constitutive null mice embryonic day 13.5 heart transcriptome |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To assess the impact of Nos1ap loss on heart transcriptome during development, RNA-seq was performed in heart tissue from wildtype (males; n=5) and Nos1ap null homozygous (males; n=5) embryonic day 13.5 (e13.5) mice, and assessed for differential gene expression. At a false discovery rate of 1% and an absolute log2-fold change over 1, only two genes (Mt2 and Gm7694) were differentially expressed. These findings indicate that constitutive loss of Nos1ap has no major widespread impact on transcriptome in e13.5 hearts.
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| |
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| Overall design |
poly-A RNA-seq in embryonic day 13.5 mouse heart from five wildtype males and five Nos1ap constitutive null males.
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| Contributor(s) |
Kapoor A, Auer DR, Chakravarti A |
| Citation(s) |
37708408 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 HL086694 |
From GWAS loci to blood pressure genes, variants & mechanisms |
NEW YORK UNIVERSITY SCHOOL OF MEDICINE |
ARAVINDA CHAKRAVARTI |
|
| Submission date |
Aug 01, 2022 |
| Last update date |
Dec 05, 2023 |
| Contact name |
Ashish Kapoor |
| Organization name |
University of Texas Health Science Center at Houston
|
| Street address |
1825 Pressler St. Rm SRB 530C
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (10)
|
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| Relations |
| BioProject |
PRJNA864854 |
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